Combined liver and kidney transplantation with particular reference to positive cytotoxic crossmatches
Year: 1989
Type: book-chapter
Abstract: Combined Liver and Kidney Transplantation with Particular Reference to Positive Cytotoxic Crossmatches SUMMARYNine patients were provided with 10 livers and 10 kidneys.Nine of the paired allografts were from the same donors.Seven of the 9 recipients are alive after 6 to 26 months.At least 3 and possibly as many as 5 of the paired transplantations were to patients whose sera possessed preformed antigraft cytotoxic antibodies.Only one of the livers seemed harmed by the antibodies, and the kidneys that were transplanted after the livers were in place were thereby seemingly protected from antibody injury in 2 of the 3 unequivocal cases.These observations may provide a clue for the development of new methods to prevent hyperacute renal rejection.
Authors: TE Starzl, Andreas G. Tzakis, L Makowka, John J. Fung, Göran B. Klintmalm, S Todo, R. D. Gordon, M Griffin
Language: English
Subfield: Transplantation
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W85560910