Psychosis of Epilepsy: a Meta-analysis
Year: 2009
Type: dissertation
Study designs: Systematic Review, Meta-Analysis
Abstract: Background The relationship between psychoses and epilepsy has been the interest of many\nstudies. Although a large number of these studies give a prevalence rate of psychosis among\nepileptic patients, to our knowledge this is the first time a meta-analysis is performed on the\nsubject. Aims The aim of this study is to do a meta-analysis to calculate the percentage of\npsychosis in epilepsy. Also, separate meta-analyses will be performed to study psychosis in\nprimary generalizes epilepsy (PGE) and in temporal lobe epilepsy (TLE). Methods Databases\nwere searched for literature that includes percentages of psychosis in epileptic patients. The\nmeta-analysis is performed with the program Comprehensive Meta-Analysis version 2.\nResults Seventeen studies were found that met the inclusion criteria. The calculated event rate\nwas 0.042 for overall epilepsy, 0.046 for PGE and 0.10 for the separate meta-analysis that\nspecifically included studies of psychosis in patients with TLE. Conclusion As expected, the\npercentage of psychosis in TLE was higher than in general epilepsy patients. In conclusion,\npsychosis appears to be occurring twice as often in epileptic patients than in the general\npopulation. Although this is a notable increase, the association between epilepsy and\npsychosis is not so high as to assume a shared final common pathway.
Author: D.R. Montagne
Language: English
Subfield: Clinical Neurology
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W89607979