Genetic and biochemical studies of the cystine-methionine series of mutants in Neurospora crassa
Year: 2003
Type: dissertation
Abstract: NOTE: Text or symbols not renderale in plain ASCII are indicated by [...]. Abstract is included in .pdf document. 1. The following enzyme activities were studied in extracts of wild type and mutant Neurospora: [...]. Activity 2 was shown to be absent in a homocysteineless mutant and activity 3 was shown to be absent in a cystathionineless mutant. It was found that a suppressor, obtained by Giles, which causes these mutants to grow on minimal, returns enzyme activity to the mutants. Each activity is shown to be catalyzed by a different enzyme. 2. Evidence is presented which indicates that a Neurospora cystathionineless mutant can synthesize cystathionine from methionine without the intervention of cysteine. 3. Mutants which are blocked between thiosulfate and cysteine are shown to grow on elemental sulfur and H[subscript 2]S.
DOI: 10.7907/fp61-bw75
Author: Fischer, Glenn Albert
Institution: California Institute of Technology
Language: English
Topic: Sulfur Compounds in Biology
Subfield: Biochemistry
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W9184971