Work

Amniotic Membrane Transplantation for Keratitis

Year: 2015

Type: article

Abstract: Keratitis without proper management tends to perforate the cornea, resulting in severe adverse consequences. In recent studies, amniotic membrane is reported to have anti-inflammatory effect and promote wound healing of corneal ulcer. Purpose: To report on the efficacy of permanent amniotic membrane transplantation (AMT) in the treatment of keratitis. Case report: A 58-year-old man with severe keratitis in both eyes caused by long term administration of topical anesthetic (alcaine) for electric ophthalmia. Single layer of amniotic membrane (AM) was placed on the defect and secured to the limbus with interrupted 10-0 nylon sutures. A bandage contact lens was applied on the AM. Postoperative medication included topical antibiotic, artificial tears and mydriatic. Three months later corticosteroid was included. There was an immediate decrease of patient’s pain after surgery. Complete epithelialization was noted after 1 month. Conclusion: AMT is an alternative adjunctive method of treatment of keratitis; it promotes epithelialization process, decreased inflammation, corneal haze and neovascularization.

Source: Journal of IMAB - Annual Proceeding (Scientific Papers)

DOI: 10.5272/jimab.2015212.784

Authors: Snezhana Murgova, Chavdar Balabanov, Mariela Oblashka

Institution: Medical University Pleven

Language: English

Topic: Corneal Surgery and Treatments

Subfield: Ophthalmology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $161