The role of microtubule-associated protein 1B in axonal growth and neuronal migration in the central nervous system.
Year: 2012
Type: review
Abstract: In this review, we discuss the role of microtubule-associated protein 1B (MAP1B) and its phosphorylation in axonal development and regeneration in the central nervous system. MAP1B exhibits similar functions during axonal development and regeneration. MAP1B and phosphorylated MAP1B in neurons and axons maintain a dynamic balance between cytoskeletal components, and regulate the stability and interaction of microtubules and actin to promote axonal growth, neural connectivity and regeneration in the central nervous system.
Source: PubMed Central
Authors: Maoguang Yang, Minfei Wu, Peng Xia, Chunxin Wang, Peng Yan, Qi Gao, Jian Liu, Haitao Wang, Xingwei Duan, Xiaoyu Yang
Institution: Jilin University
Language: English
Subfield: Cellular and Molecular Neuroscience
Field: Neuroscience
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W972431487