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Оценка степени цитотоксичности компонентов патологических сывороток с использованием клеточной тест-системы

Year: 2010

Type: article

Abstract: Screening indication of blood serum cytotoxicity with a testsystem based on monocellular algae Dunaliella viridis was carried out. Significant differences of morphological and functional parameters D. viridis, induced by cytotoxic factors of various nature were detected. Patterns of morphological and functional changes of the bioindicator cells in the coordinate system were defined. Coefficients of toxicity for investigated biological liquids are calculated. Maximum degree of cytotoxicity was revealed in blood serum received from the patients suffering from biliary cirrhosis ( К Ц = 13,01±01) and myasthenia ( К Ц = 11,6±0,76), minimal one ( К Ц = 5,65±0,66) was with acute varicothrombosis.

Source: Biotechnologia Acta

Authors: Elena Martínez‐Klimova, Е. В. Лавинская, А. І. Божков, Т. И. Кордон

Language: Russian

Topic: Environmental Toxicology and Ecotoxicology

Subfield: Health, Toxicology and Mutagenesis

Field: Environmental Science

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W99359039

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