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Sesquiterpenes with Quinone Reductase-Inducing Activity from Liriodendron Chinense

Year: 2009

Type: article

Abstract: Bioassay-directed separation of the methylene chloride extracts from the wood of Liriodendron chinense led to the isolation of six sesquiterpenes, tulipinolide (1), alpha-liriodenolide (2), beta-liriodenolide (3), lipiferolide (4), 11,13-dehydrolanuginolide (5), and tulipinolide diepoxide (6). Compounds 1-6 have not been found previously in L. chinense. The structures of the compounds were established on the basis of NMR spectroscopic data. All the compounds exhibited quinone reductase (QR)-inducing activity in Hepa lclc7 cells.

Source: Natural Product Communications

DOI: 10.1177/1934578x0900400403

Authors: Ying Dong, Dong Liang, Jianjin Huang, Peng Zhang

Institutions: Second Affiliated Hospital of Zhejiang University, Zhejiang University, Shenyang Pharmaceutical University

Language: English

Topic: Sesquiterpenes and Asteraceae Studies

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: bronze

OpenAlex ID: W99418790

FWCI:

Cites: 6

Cited by: 3

Related to: 10