Vector integration is nonrandom and clustered and influences the fate of lymphopoiesis in SCID-X1 gene therapy
Work
Year: 2007
Type: article
Abstract: Recent reports have challenged the notion that retroviruses and retroviral vectors integrate randomly into the host genome. These reports pointed to a strong bias toward integration in and near gene c... more
Authors Annette Deichmann, Salima Hacein‐Bey‐Abina, Manfred Schmidt, Alexandrine Garrigue, Martijn H. Brugman +27 more
Institutions German Cancer Research Center, Université Paris Cité, University of Freiburg, Erasmus University Rotterdam, Takeda (Japan) +8 more
Cites: 34
Cited by: 256
Related to: 10
FWCI: 16.11
Citation percentile (by year/subfield): 99.99
Subfield: Genetics
Domain: Life Sciences
Open Access status: bronze