Product
Help
Pricing
About
Jobs
Log in
Get started
Author
Add to collection
Robert Godemann
Observed names:
R. Godemann,
Robert Godemann Aventis
Institution:
Evotec (Germany)
Observed institutions:
Ipsen (France),
Evotec (Germany),
Evotec (United Kingdom),
Max Planck Unit for Structural Molecular Biology,
Evotec (United States)
OpenAlex ID:
A5017579545
Overexpression of Tau Protein Inhibits Kinesin-dependent Trafficking of Vesicles, Mitochondria, and Endoplasmic Reticulum: Implications for Alzheimer's Disease
1998
·
A. Ebneth
, R. Godemann
, et al.
·
The Journal of Cell Biology
·
829
Sequential phosphorylation of Tau by glycogen synthase kinase‐3β and protein kinase A at Thr212 and Ser214 generates the Alzheimer‐specific epitope of antibody AT100 and requires a paired‐helical‐filament‐like conformation
1998
·
Qingyi Zheng‐Fischhöfer
, Jacek Biernat
, et al.
·
European Journal of Biochemistry
·
336
PDF
The Endogenous and Cell Cycle-dependent Phosphorylation of tau Protein in Living Cells: Implications for Alzheimer’s Disease
1998
·
Susanne Illenberger
, Qingyi Zheng-Fischhöfer
, et al.
·
Molecular Biology of the Cell
·
305
NF-κB inducing kinase is a therapeutic target for systemic lupus erythematosus
2018
·
Hans D. Brightbill
, Eric Suto
, et al.
·
Nature Communications
·
132
PDF
Phosphorylation of tau protein by recombinant GSK‐3β: pronounced phosphorylation at select Ser/Thr‐Pro motifs but no phosphorylation at Ser262 in the repeat domain
1999
·
R. Godemann
, J. Biernat
, et al.
·
FEBS Letters
·
110
PDF
Structure-Based Design of Tricyclic NF-κB Inducing Kinase (NIK) Inhibitors That Have High Selectivity over Phosphoinositide-3-kinase (PI3K)
2016
·
Georgette M. Castanedo
, Nicole Blaquiere
, et al.
·
Journal of Medicinal Chemistry
·
65
Early-Onset and Robust Amyloid Pathology in a New Homozygous Mouse Model of Alzheimer's Disease
2009
·
Antje Willuweit
, Joachim Velden
, et al.
·
PLoS ONE
·
60
PDF
The multiple roles of computational chemistry in fragment-based drug design
2009
·
Richard Law
, Oliver Barker
, et al.
·
Journal of Computer-Aided Molecular Design
·
60
Scaffold-Hopping Approach To Discover Potent, Selective, and Efficacious Inhibitors of NF-κB Inducing Kinase
2018
·
Nicole Blaquiere
, Georgette M. Castanedo
, et al.
·
Journal of Medicinal Chemistry
·
57
Fragment-Based Discovery of BACE1 Inhibitors Using Functional Assays
2009
·
Robert Godemann
, James Madden
, et al.
·
Biochemistry
·
52
PDF
Fragment-based discovery and optimization of BACE1 inhibitors
2010
·
James Madden
, Jenny R. Dod
, et al.
·
Bioorganic & Medicinal Chemistry Letters
·
42
Structure Based Design of Potent Selective Inhibitors of Protein Kinase D1 (PKD1)
2019
·
Jianwen A. Feng
, Patrick Lee
, et al.
·
ACS Medicinal Chemistry Letters
·
10
Filling a nick in NIK: Extending the half-life of a NIK inhibitor through structure-based drug design
2023
·
James J. Crawford
, Jianwen Feng
, et al.
·
Bioorganic & Medicinal Chemistry Letters
·
7
Tau Protein: Role in Intracellular Traffic and Development of Cell Polarity
2000
·
E.-M. Mandelkow
, J. Biernat
, et al.
·
Research and perspectives in Alzheimer's disease
·
2
Selective inhibition of NF-kB inducing kinase (NIK) is therapeutically efficacious in IFNα-accelerated lupus nephritis prone mice
2017
·
Hans D Brightbill
, Eric Suto
, et al.
·
The Journal of Immunology
·
1
Structure of Bace (beta secretase) in complex with ligand EV2
2009
·
R. Godemann
, J. Madden
, et al.
·
Worldwide Protein Data Bank
Structure of bace (beta secretase) in Complex with EV0
2009
·
R. Godemann
, J. Madden
, et al.
·
Worldwide Protein Data Bank
Tau protein and Alzheimer's disease: Phosphorylation and role in intracellular trafficking
2000
·
Eva-Maria Mandelkow
, Andreas Ebneth
, et al.
·
Neurobiology of Aging
513 Phosphorylation of tau by GSK3 and effects on microtubule dynamics
1996
·
R. Godemann
, G. Schmitt-Ulms
, et al.
·
Neurobiology of Aging
Show more works
View as search
Works count:
21
Citation count:
2,068
H-index:
11
I10-index:
12
Year
Topic
Type