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Mario Kuttke
Observed name:
M. Kuttke
Institution:
Vienna Biocenter
Observed institutions:
University Health Network,
Research Institute of Molecular Pathology,
Princess Margaret Cancer Centre,
University of California San Diego,
Comprehensive Cancer Center Vienna,
Vienna Biocenter,
Medical University of Vienna
show all 7
ORCID:
0000-0003-3517-2841
Observed ORCID:
0000-0003-3517-2841
OpenAlex ID:
A5019047983
Acquired resistance to anti-MAPK targeted therapy confers an immune-evasive tumor microenvironment and cross-resistance to immunotherapy in melanoma
2021
·
Lisa Haas
, Anais Elewaut
, et al.
·
Nature Cancer
·
207
Macrophage PTEN Regulates Expression and Secretion of Arginase I Modulating Innate and Adaptive Immune Responses
2014
·
Emine Sahin
, Stefan Haubenwallner
, et al.
·
The Journal of Immunology
·
159
PDF
Oral activity of a nature-derived cyclic peptide for the treatment of multiple sclerosis
2016
·
Kathrin Thell
, Roland Hellinger
, et al.
·
Proceedings of the National Academy of Sciences
·
146
PDF
Sustained PI3K Activation exacerbates BLM-induced Lung Fibrosis via activation of pro-inflammatory and pro-fibrotic pathways
2016
·
Julia Barbara Kral
, Mario Kuttke
, et al.
·
Scientific Reports
·
82
PDF
Fab antibody fragment-functionalized liposomes for specific targeting of antigen-positive cells
2017
·
Anna Ohradanova-Repic
, Eugénia Nogueira
, et al.
·
Nanomedicine Nanotechnology Biology and Medicine
·
54
Food-derived peroxidized fatty acids may trigger hepatic inflammation: A novel hypothesis to explain steatohepatitis
2013
·
Therese Böhm
, Heidi Berger
, et al.
·
Journal of Hepatology
·
54
The PI3K pathway preserves metabolic health through MARCO-dependent lipid uptake by adipose tissue macrophages
2020
·
Julia S. Brunner
, Andrea Vogel
, et al.
·
Nature Metabolism
·
45
JAK1 signaling in dendritic cells promotes peripheral tolerance in autoimmunity through PD-L1-mediated regulatory T cell induction
2022
·
Andrea Vogel
, Katharina Martin
, et al.
·
Cell Reports
·
42
PDF
Proteomic Profiling of Advanced Melanoma Patients to Predict Therapeutic Response to Anti-PD-1 Therapy
2023
·
Nina Zila
, Ossia M. Eichhoff
, et al.
·
Clinical Cancer Research
·
26
Macrophage Phosphoproteome Analysis Reveals MINCLE-dependent and -independent Mycobacterial Cord Factor Signaling
2019
·
Madlen Hansen
, Julian Peltier
, et al.
·
Molecular & Cellular Proteomics
·
25
PDF
Potential of unglycosylated horseradish peroxidase variants for enzyme prodrug cancer therapy
2021
·
Diana Humer
, Valentina Furlanetto
, et al.
·
Biomedicine & Pharmacotherapy
·
24
PDF
Ikk2-mediated inflammatory activation of arterial endothelial cells promotes the development and progression of atherosclerosis
2020
·
Marion Mussbacher
, Manuel Salzmann
, et al.
·
Atherosclerosis
·
18
Platelet p110β mediates platelet-leukocyte interaction and curtails bacterial dissemination in pneumococcal pneumonia
2022
·
Waltraud Cornelia Schrottmaier
, Julia Barbara Kral-Pointner
, et al.
·
Cell Reports
·
17
Myeloid PTEN deficiency impairs tumor-immune surveillance via immune-checkpoint inhibition
2016
·
M. Kuttke
, E. Sahin
, et al.
·
OncoImmunology
·
14
Loss of Phosphatase and Tensin Homolog in APCs Impedes Th17-Mediated Autoimmune Encephalomyelitis
2015
·
Emine Sahin
, Julia S Brunner
, et al.
·
The Journal of Immunology
·
12
PI3K Signaling in Dendritic Cells Aggravates DSS-Induced Colitis
2022
·
Mario Kuttke
, Dominika Hromadová
, et al.
·
Frontiers in Immunology
·
10
Loss of MAPK-activated protein kinase 2 enables potent dendritic cell-driven anti-tumour T cell response
2017
·
Klara Soukup
, Angela Halfmann
, et al.
·
Scientific Reports
·
10
PDF
Erratum: Sustained PI3K Activation exacerbates BLM-induced Lung Fibrosis via activation of pro-inflammatory and pro-fibrotic pathways
2016
·
Julia Barbara Kral
, Mario Kuttke
, et al.
·
Scientific Reports
·
8
PDF
TAT-MeCP2 protein variants rescue disease phenotypes in human and mouse models of Rett syndrome
2022
·
Hannes Steinkellner
, Prakasha Kempaiah
, et al.
·
International Journal of Biological Macromolecules
·
7
Master checkpoint Cbl-b inhibition: Anti-tumour efficacy in a murine colorectal cancer model following siRNA-based cell therapy
2019
·
K. Thell
, M. Urban
, et al.
·
Annals of Oncology
·
6
PDF
Correction: Macrophage PTEN Regulates Expression and Secretion of Arginase I Modulating Innate and Adaptive Immune Responses
2014
·
Emine Sahin
, Stefan Haubenwallner
, et al.
·
The Journal of Immunology
·
4
Abstract LB187: Case report: APN401, a novel cancer therapy using Cbl-b silenced autologous PBMCs, induced stable disease in two patients with advanced solid tumors
2023
·
Mario Kuttke
, Alexander Dohnal
, et al.
·
Cancer Research
·
2
Cblb Gene Editing in T Cells Sustains Expansion and Immunogenic CAR T Tumor Killing Under Chronic Antigenic Stimulation
2026
·
Daniel Schreiber
, Sebastian Peer
, et al.
·
Cells
·
1
Supplementary Table S1 from Proteomic Profiling of Advanced Melanoma Patients to Predict Therapeutic Response to Anti-PD-1 Therapy
2024
·
Nina Zila
, Ossia M. Eichhoff
, et al.
·
1
PDF
Phase 1 evaluation of APN401, an autologous CBL-B-silenced PBMC therapy, in advanced solid tumors
2026
·
Alexander Dohnal
, Nina Worel
, et al.
·
Molecular Therapy Oncology
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Works count:
53
Citation count:
974
H-index:
14
I10-index:
17
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