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Author

Valentina Varela

Observed name: Varela, Valentina
Observed institution: Institut Pasteur de Montevideo
ORCID: 0000-0002-5718-0474
Observed ORCID: 0000-0002-5718-0474
OpenAlex ID: A5027678782
Mast cells and neutrophils mediate peripheral motor pathway degeneration in ALS
2018 · Emiliano Trias, Peter H. King, et al. · JCI Insight · 145
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Emergence of Microglia Bearing Senescence Markers During Paralysis Progression in a Rat Model of Inherited ALS
2019 · Emiliano Trias, Pamela R. Beilby, et al. · Frontiers in Aging Neuroscience · 89
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Evidence for mast cells contributing to neuromuscular pathology in an inherited model of ALS
2017 · Emiliano Trias, Sofía Ibarburu, et al. · JCI Insight · 82
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Schwann cells orchestrate peripheral nerve inflammation through the expression of CSF1, IL‐34, and SCF in amyotrophic lateral sclerosis
2019 · Emiliano Trias, Mariángeles Kovacs, et al. · Glia · 79
PD-1/PD-L1 blockade abrogates a dysfunctional innate-adaptive immune axis in critical β-coronavirus disease
2022 · Maite Duhalde Vega, Daniela Olivera, et al. · Science Advances · 26
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The pathogenic role of c-Kit+ mast cells in the spinal motor neuron-vascular niche in ALS
2021 · Mariángeles Kovacs, Catalina Alamón, et al. · Acta Neuropathologica Communications · 21
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A Nitroalkene Benzoic Acid Derivative Targets Reactive Microglia and Prolongs Survival in an Inherited Model of ALS via NF-κB Inhibition
2020 · Sofía Ibarburu, Mariángeles Kovacs, et al. · Neurotherapeutics · 15
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CD34 Identifies a Subset of Proliferating Microglial Cells Associated with Degenerating Motor Neurons in ALS
2019 · Mariángeles Kovacs, Emiliano Trias, et al. · International Journal of Molecular Sciences · 14
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Focal Transplantation of Aberrant Glial Cells Carrying the SOD1G93A Mutation into Rat Spinal Cord Induces Extensive Gliosis
2017 · Sofía Ibarburu, Emiliano Trias, et al. · NeuroImmunoModulation · 12
Monoclonal antibodies against nitrated nerve growth factor reveal an oxidation-dependent pathogenic hallmark in ALS
2026 · Valentina Varela, Santiago Garcimartín, et al. · Proceedings of the National Academy of Sciences · 1
Production and characterization of rNGFSP: a recombinant fusion immunogen eliciting dual anti-NGF and anti-Substance P therapeutic antibodies for Degenerative Joint Disease
2026 · Valentina Varela, Monique Costa, et al. · Biotechnology Reports · 1
Nitrated Nerve Growth Factor (NO2NGF) as a Pathogenic Hallmark in Neurodegenerative Diseases
2026 · Santiago Garcimartin, Nicolás Campolo, et al. · Free Radical Biology and Medicine
Increased nitrated nerve growth factor as a hallmark in amyotrophic lateral sclerosis
2026 · Santiago Garcimartín, Valentina Varela, et al. · Free Radical Biology and Medicine
A neutralizing antibody and a p75NTR inhibitor prevent neuronal apoptosis induced by oxidatively modified NGF
2025 · Santiago Garcimartin, Nicolas Campolo, et al. · Free Radical Biology and Medicine
Peroxynitrite transforms Nerve Growth Factor (NGF) to a pro-apoptotic factor for cortical neurons: Possible implications in Alzheimer’s disease
2025 · Santiago Garcimartín, Nicolas Campolo, et al. · Free Radical Biology and Medicine
Mast Cells and Mast Cell Precursors Accumulate in the Pathogenic Alzheimer’s Disease Brain
2023 · Emiliano Trias, Mariángeles Kovacs, et al. · IBRO Neuroscience Reports
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Desarrollo y caracterización de anticuerpos monoclonales para el factor de crecimiento nervioso (NGF) modificado post traduccionalmente por nitración en residuos de tirosina
2017 · Valentina Varela · LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas)
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Works count: 19
Citation count: 485
H-index: 9
I10-index: 9
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