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Akiyoshi Tani

ORCID: 0000-0001-6578-844X
Observed ORCID: 0000-0001-6578-844X
OpenAlex ID: A5035961731
K-Ras(G12D)-selective inhibitory peptides generated by random peptide T7 phage display technology
2017 · Kotaro Sakamoto, Yusuke Kamada, et al. · Biochemical and Biophysical Research Communications · 121
Trelagliptin (SYR-472, Zafatek), Novel Once-Weekly Treatment for Type 2 Diabetes, Inhibits Dipeptidyl Peptidase-4 (DPP-4) via a Non-Covalent Mechanism
2016 · Charles E. Grimshaw, Andy Jennings, et al. · PLoS ONE · 64
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Discovery of GPX4 inhibitory peptides from random peptide T7 phage display and subsequent structural analysis
2016 · Kotaro Sakamoto, Satoshi Sogabe, et al. · Biochemical and Biophysical Research Communications · 60
Celastrol suppresses humoral immune responses and autoimmunity by targeting the COMMD3/8 complex
2023 · Taiichiro Shirai, Akiko Nakai, et al. · Science Immunology · 59
Discovery of a 3-Pyridylacetic Acid Derivative (TAK-100) as a Potent, Selective and Orally Active Dipeptidyl Peptidase IV (DPP-4) Inhibitor
2011 · Yasufumi Miyamoto, Yoshihiro Banno, et al. · Journal of Medicinal Chemistry · 55
Design, synthesis, and structure–activity relationships of novel spiro-piperidines as acetyl-CoA carboxylase inhibitors
2012 · Makoto Kamata, Tohru Yamashita, et al. · Bioorganic & Medicinal Chemistry Letters · 53
Identification of 3-aminomethyl-1,2-dihydro-4-phenyl-1-isoquinolones: A new class of potent, selective, and orally active non-peptide dipeptidyl peptidase IV inhibitors that form a unique interaction with Lys554
2011 · Yoshihiro Banno, Yasufumi Miyamoto, et al. · Bioorganic & Medicinal Chemistry · 44
Symmetrical approach of spiro-pyrazolidinediones as acetyl-CoA carboxylase inhibitors
2012 · Makoto Kamata, Tohru Yamashita, et al. · Bioorganic & Medicinal Chemistry Letters · 42
Discovery of potent, selective, and orally bioavailable quinoline-based dipeptidyl peptidase IV inhibitors targeting Lys554
2011 · Hironobu Maezaki, Yoshihiro Banno, et al. · Bioorganic & Medicinal Chemistry · 30
Restoration of Cardiac Myosin Light Chain Kinase Ameliorates Systolic Dysfunction by Reducing Superrelaxed Myosin
2023 · Tatsuro Hitsumoto, Osamu Tsukamoto, et al. · Circulation · 28
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Tetracyclines enhance antitumor T-cell immunity via the Zap70 signaling pathway
2024 · Mari Tone, Kota Iwahori, et al. · Journal for ImmunoTherapy of Cancer · 26
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Establishment of a novel human CIC-DUX4 sarcoma cell line, Kitra-SRS, with autocrine IGF-1R activation and metastatic potential to the lungs
2019 · Sho Nakai, Shutaro Yamada, et al. · Scientific Reports · 26
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Design and synthesis of 3-pyridylacetamide derivatives as dipeptidyl peptidase IV (DPP-4) inhibitors targeting a bidentate interaction with Arg125
2010 · Yasufumi Miyamoto, Yoshihiro Banno, et al. · Bioorganic & Medicinal Chemistry · 25
Design of potent dipeptidyl peptidase IV (DPP-4) inhibitors by employing a strategy to form a salt bridge with Lys554
2017 · Hironobu Maezaki, Michiko Tawada, et al. · Bioorganic & Medicinal Chemistry Letters · 24
Design, synthesis, and structure–activity relationships of spirolactones bearing 2-ureidobenzothiophene as acetyl-CoA carboxylases inhibitors
2011 · Tohru Yamashita, Makoto Kamata, et al. · Bioorganic & Medicinal Chemistry Letters · 19
Discovery of artificial VIPR2-antagonist peptides possessing receptor- and ligand-selectivity
2018 · Kotaro Sakamoto, Ryokichi Koyama, et al. · Biochemical and Biophysical Research Communications · 16
Investigation on cellular uptake and pharmacodynamics of DOCK2-inhibitory peptides conjugated with cell-penetrating peptides
2017 · Yusuke Adachi, Kotaro Sakamoto, et al. · Bioorganic & Medicinal Chemistry · 13
Synthesis and biochemical characterization of naphthoquinone derivatives targeting bacterial histidine kinases
2024 · Teruhiko Ishikawa, Yoko Eguchi, et al. · The Journal of Antibiotics · 8
Identification of cytidine-5-triphosphate synthase1-selective inhibitory peptide from random peptide library displayed on T7 phage
2017 · Kotaro Sakamoto, Yoshihiro Ishibashi, et al. · Peptides · 8
Microtubule inhibitors identified through nonbiased screening enhance DNA transfection efficiency by delaying p62‐dependent ubiquitin recruitment
2021 · Megumi Tsuchiya, Hidesato Ogawa, et al. · Genes to Cells · 3
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Corrigendum to “Symmetrical approach of spiro-pyrazolidinediones as acetyl-CoA carboxylase inhibitors” [Bioorg. Med. Chem. Lett. 22 (2012) 4769–4772]
2012 · Makoto Kamata, Tohru Yamashita, et al. · Bioorganic & Medicinal Chemistry Letters · 3
Development of EIA systems for active-form MAP kinase
2000 · Akiyoshi Tani, Masakuni Noda, et al. · Journal of Immunological Methods · 3
Author Correction: Establishment of a novel human CIC-DUX4 sarcoma cell line, Kitra-SRS, with autocrine IGF-1R activation and metastatic potential to the lungs
2020 · Sho Nakai, Shutaro Yamada, et al. · Scientific Reports · 2
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Corrigendum to “Discovery of potent, selective, and orally bioavailable quinoline-based dipeptidyl peptidase IV inhibitors targeting Lys554” [Bioorg. Med. Chem. 19 (2011) 4482–4498]
2011 · Hironobu Maezaki, Yoshihiro Banno, et al. · Bioorganic & Medicinal Chemistry · 2
Correction: Amino acid mapping–guided scaffold selection and hit identification of histidine kinase inhibitors from a virtual library of over 12 million compounds
2026 · Teruhiko Ishikawa, Yoko Eguchi, et al. · The Journal of Antibiotics
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Works count: 29
Citation count: 733
H-index: 16
I10-index: 17
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