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Helena Chaytow
Observed name:
Chaytow, Helena
Institutions:
Euan MacDonald Centre for Motor Neuron Disease Research,
University of Edinburgh
Observed institutions:
Goethe University Frankfurt,
Royal Holloway University of London,
Euan MacDonald Centre for Motor Neuron Disease Research,
Roskamp Institute,
Cardiff University,
University of Edinburgh
show all 6
ORCID:
0000-0003-2257-7620
Observed ORCID:
0000-0003-2257-7620
OpenAlex ID:
A5085898310
Repetitive Mild Traumatic Brain Injury in a Mouse Model Produces Learning and Memory Deficits Accompanied by Histological Changes
2012
·
Benoit Mouzon
, Helena Chaytow
, et al.
·
Journal of Neurotrauma
·
301
PDF
The role of survival motor neuron protein (SMN) in protein homeostasis
2018
·
Helena Chaytow
, Yu-Ting Huang
, et al.
·
Cellular and Molecular Life Sciences
·
241
PDF
Spinal muscular atrophy: From approved therapies to future therapeutic targets for personalized medicine
2021
·
Helena Chaytow
, Kiterie M.E. Faller
, et al.
·
Cell Reports Medicine
·
182
PDF
AI is a viable alternative to high throughput screening: a 318-target study
2024
·
The Atomwise AIMS Program
, Izhar Wallach
, et al.
·
Scientific Reports
·
149
Brain‐derived neurotropic factor polymorphisms, traumatic stress, mild traumatic brain injury, and combat exposure contribute to postdeployment traumatic stress
2015
·
Michael N. Dretsch
, Kathy Williams
, et al.
·
Brain and Behavior
·
73
PDF
Small junction, big problems: Neuromuscular junction pathology in mouse models of amyotrophic lateral sclerosis (ALS)
2021
·
Abrar Alhindi
, Ines Boehm
, et al.
·
Journal of Anatomy
·
72
PDF
Targeting phosphoglycerate kinase 1 with terazosin improves motor neuron phenotypes in multiple models of amyotrophic lateral sclerosis
2022
·
Helena Chaytow
, Emily Carroll
, et al.
·
EBioMedicine
·
60
Plasma Lipidomic Profiling in a Military Population of Mild Traumatic Brain Injury and Post-Traumatic Stress Disorder with Apolipoprotein E ɛ4–Dependent Effect
2015
·
Tanja Emmerich
, Laila Abdullah
, et al.
·
Journal of Neurotrauma
·
55
Pre-natal manifestation of systemic developmental abnormalities in spinal muscular atrophy
2020
·
Anna A L Motyl
, Kiterie M E Faller
, et al.
·
Human Molecular Genetics
·
46
PDF
Revisiting the role of mitochondria in spinal muscular atrophy
2021
·
Rachel James
, Helena Chaytow
, et al.
·
Cellular and Molecular Life Sciences
·
45
PDF
Targeting common disease pathomechanisms to treat amyotrophic lateral sclerosis
2025
·
Kiterie M. E. Faller
, Helena Chaytow
, et al.
·
Nature Reviews Neurology
·
31
Genetics and Other Risk Factors for Past Concussions in Active-Duty Soldiers
2016
·
Michael N. Dretsch
, Noah Silverberg
, et al.
·
Journal of Neurotrauma
·
23
Automated in vivo drug screen in zebrafish identifies synapse-stabilising drugs with relevance to spinal muscular atrophy
2021
·
Ana-Maria Oprişoreanu
, Hannah L. Smith
, et al.
·
Disease Models & Mechanisms
·
22
The mitochondrial protein Sideroflexin 3 (SFXN3) influences neurodegeneration pathways in vivo
2022
·
Leire M. Ledahawsky
, Maria Eirini Terzenidou
, et al.
·
FEBS Journal
·
18
PDF
Neuromuscular junction denervation and terminal Schwann cell loss in the hTDP‐43 overexpression mouse model of amyotrophic lateral sclerosis
2023
·
Abrar Alhindi
, Megan Shand
, et al.
·
Neuropathology and Applied Neurobiology
·
17
PDF
The CCL2-CCR2 axis drives neuromuscular denervation in amyotrophic lateral sclerosis
2025
·
Bernát Nógrádi
, Kinga Molnár
, et al.
·
Nature Communications
·
13
PDF
Phosphoglycerate kinase 1 as a therapeutic target in neurological disease
2025
·
Harriet McHale-Owen
, Kiterie M.E. Faller
, et al.
·
Trends in Molecular Medicine
·
13
Excitotoxicity and ALS: New therapy targets an old mechanism
2024
·
Hannah Louise Smith
, Helena Chaytow
, et al.
·
Cell Reports Medicine
·
10
Prenatal SMN-dependent defects in translation uncover reversible primary cilia phenotypes in spinal muscular atrophy
2025
·
Federica Genovese
, Yu-Ting Huang
, et al.
·
JCI Insight
·
6
Timing of SMN replacement therapies in mouse models of spinal muscular atrophy: a systematic review and meta-analysis
2024
·
Helena Chaytow
, Anna A L Motyl
, et al.
·
Brain Communications
·
6
PDF
Long-term muscle-specific overexpression of DOK7 in mice using AAV9-tMCK-DOK7
2023
·
Yu-Ting Huang
, Hannah R. Crick
, et al.
·
Molecular Therapy — Nucleic Acids
·
6
PDF
Author Correction: AI is a viable alternative to high throughput screening: a 318-target study
2024
·
The Atomwise AIMS Program
, Izhar Wallach
, et al.
·
Scientific Reports
·
3
PDF
A new strategy to increase RNA editing at the Q/R site of GluA2 AMPA receptor subunits by targeting alternative splicing patterns of ADAR2
2021
·
Helena Chaytow
, Ilda Sethw Hassan
, et al.
·
Journal of Neuroscience Methods
·
2
PDF
Dynamic modulation of the motor neuron translatome during developmental synapse elimination
2025
·
Dinja van der Hoorn
, Fabio Lauria
, et al.
·
Science Signaling
·
1
Mifepristone alone and in combination with scAAV9-SMN1 gene therapy improves disease phenotypes in Smn2B/- spinal muscular atrophy mice
2025
·
Emma R. Sutton
, Eve McCallion
, et al.
·
Scientific Reports
PDF
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Works count:
31
Citation count:
1,395
H-index:
15
I10-index:
18
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