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Author

Ehab E Sharata

Observed name: Ehab E. Sharata
Institution: Deraya University
Observed institution: Deraya University
ORCID: 0009-0002-6517-7221
Observed ORCID: 0009-0002-6517-7221
OpenAlex ID: A5091966197
LCZ696 (sacubitril/valsartan) mitigates cyclophosphamide-induced premature ovarian failure in rats; the role of TLR4/NF-κB/NLRP3/Caspase-1 signaling pathway
2023 · Waleed A.I. Khallaf, Ehab E. Sharata, et al. · Life Sciences · 47
Buspirone ameliorates premature ovarian insufficiency evoked by cyclophosphamide in female rats; attention to AMPK/Nrf2/HO-1, α-Klotho/NLRP3/Caspase-1, and Caspase-3-mediated apoptosis interplay
2025 · Waleed A.I. Khallaf, Ehab E. Sharata, et al. · Toxicology and Applied Pharmacology · 39
Molecular mechanisms underlying cyclophosphamide-induced ovarian injury and protective strategies
2025 · Ehab E. Sharata, Taha Bakry, et al. · Naunyn-Schmiedeberg s Archives of Pharmacology · 34
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Repurposing levomilnacipran to attenuate premature ovarian insufficiency induced by cyclophosphamide in female Wistar albino rats through modulation of TLR4/p38-MAPK/NF-κB p65, caspase-3-driven apoptosis, and Klotho protein expression
2025 · Remon Roshdy Rofaeil, Ehab E. Sharata, et al. · Food and Chemical Toxicology · 29
LCZ696 attenuates sepsis-induced liver dysfunction in rats; the role of oxidative stress, apoptosis, and JNK1/2-P38 signaling pathways
2023 · Reham H. Mohyeldin, Rania Alaaeldin, et al. · Life Sciences · 29
Aprepitant boasted a protective effect against olanzapine-induced metabolic syndrome and its subsequent hepatic, renal, and ovarian dysfunction; Role of IGF1/p-AKT/FOXO1 and NFκB/IL-1β/TNF-α signaling pathways in female Wistar albino rats
2024 · Reham H. Mohyeldin, Walaa Yehia Abdelzaher, et al. · Biochemical Pharmacology · 28
Decoding premature ovarian insufficiency: A full spectrum review from epidemiology to management with emphasis on cyclophosphamide-evoked ovarian injury
2025 · Ehab E. Sharata, Mina Ezzat Attya, et al. · Food and Chemical Toxicology · 26
Apremilast ameliorates methotrexate-induced renal injury in rats: role of TLR4/NF-κB/P38 MAPK/caspase-3 and Nrf2/HO-1 signaling pathways
2025 · Reham H. Mohyeldin, Ehab E. Sharata, et al. · Naunyn-Schmiedeberg s Archives of Pharmacology · 22
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Unraveling chemotherapy-evoked hepatic dysfunction: a deep dive into cyclophosphamide-related liver injury
2025 · Ehab E. Sharata, Mina Ezzat Attya, et al. · Naunyn-Schmiedeberg s Archives of Pharmacology · 22
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Buspirone combats cyclophosphamide-provoked hepatotoxicity in rats via activation of AMPK/Nrf2/HO-1 and suppression of NF-κB p65 /NLRP3 inflammasome pathways
2025 · Marwa M. Khalaf, Ehab E. Sharata, et al. · Naunyn-Schmiedeberg s Archives of Pharmacology · 21
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Apremilast attenuates methotrexate-induced hepatic injury in rats; insights into TLR4/NF-κB/P38 MAPK/caspase-3 and α-klotho/Nrf2/HO-1 signaling network interplay
2025 · Reham H. Mohyeldin, Ehab E. Sharata, et al. · Toxicology and Applied Pharmacology · 21
Memantine abrogates testicular dysfunction induced by risperidone in rats with a potential role of ERK1/2-Nrf2-caspase-3 signaling pathway
2025 · Reham H. Mohyeldin, Ehab E. Sharata, et al. · Scientific Reports · 21
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Levomilnacipran alleviates cyclophosphamide-induced hepatic dysfunction in male Wistar albino rats; emerging role of α-Klotho/TLR4/p38-MAPK/NF-κB p65 and caspase-3-driven apoptosis trajectories
2025 · Ehab E. Sharata, Mina Ezzat Attya, et al. · International Immunopharmacology · 21
The protective effect of vinpocetine against Estradiol-benzoate induced cervical hyperkeratosis in female rats via modulation of SIRT1/Nrf2, and NLRP3 inflammasome
2024 · Remon R. Rofaeil, Reham H. Mohyeldin, et al. · Scientific Reports · 17
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Vincamine exerts hepato-protective activity during colon ligation puncture-induced sepsis by modulating oxidative stress, apoptosis, and TNFα/Nrf-2/Keap-1 signaling pathways
2024 · Rania Alaaeldin, Reham H. Mohyeldin, et al. · Scientific Reports · 16
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Modulating platelet-activating factor by rupatadine attenuates gentamicin-induced nephrotoxicity in rats via NF-κB/caspase-3 and Nrf2/HO-1 signaling cascades
2025 · Reham H. Mohyeldin, Mahmoud Abdelnaser, et al. · Naunyn-Schmiedeberg s Archives of Pharmacology · 15
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Atomoxetine attenuates methotrexate-induced lung injury in rats implicating TLR4/NF-κB and Bax/Bcl-2/caspase-3 signaling cascades: a study based on molecular docking and experimental validation
2026 · Reham H. Mohyeldin, Ehab E. Sharata, et al. · Naunyn-Schmiedeberg s Archives of Pharmacology · 4
Decoding polycystic ovary syndrome: an integrated review of epidemiology, molecular mechanisms, animal models, and the expanding therapeutic landscape
2026 · Ehab E. Sharata, Ahmed S. Abdel-Samea, et al. · Naunyn-Schmiedeberg s Archives of Pharmacology · 3
Programmable multi-stimuli photonic hydrogels for intelligent and adaptive transdermal drug delivery
2026 · Mahmoud Mohamed Omar, Ramadan A. M. Hemeida, et al. · Discover Applied Sciences · 2
Imeglimin halts cyclophosphamide-induced ovarian injury: a dual modulation of TLR4/NF-κB/NLRP3-driven inflammation and AMPK/SIRT1/PGC-1α pathways
2026 · Reham H. Mohyeldin, Ehab E. Sharata, et al. · Naunyn-Schmiedeberg s Archives of Pharmacology · 1
Deciphering gentamicin-induced nephrotoxicity and hepatotoxicity: Pathophysiological insights and emerging protective approaches
2026 · Ehab E. Sharata, Reham H. Mohyeldin, et al. · Food and Chemical Toxicology · 1
Current perspectives on natural and pharmacological interventions for combating drug-induced pulmonary toxicity
2026 · Ehab E. Sharata, Mahmoud Abdelnaser, et al. · Naunyn-Schmiedeberg s Archives of Pharmacology · 1
Ulcerative colitis: from molecular pathophysiology to management and the emerging role of natural and pharmacological drug candidates
2026 · Ehab E. Sharata, Taha Bakry, et al. · Naunyn-Schmiedeberg s Archives of Pharmacology · 1
Piracetam attenuates cyclophosphamide-evoked pulmonary injury in rats; the role of AMPK/NF-κB/NLRP3/caspase-1 and caspase-3 mediated apoptosis signaling cascades
2026 · Reham H. Mohyeldin, Ehab E. Sharata, et al. · Scientific Reports
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Vonoprazan attenuates cyclophosphamide-induced ovarian injury in rats via modulation of TLR4/NF-κB and AMPK/SIRT1/Nrf2/HO-1 signaling
2026 · Al Shaimaa Mahmoud Kotb, Ehab E. Sharata, et al. · Tissue and Cell
Works count: 29
Citation count: 421
H-index: 15
I10-index: 16
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