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Mahmoud S. Elkotamy

Observed names: Elkotamy, Mahmoud S., Mahmoud Elkotamy, Mahmoud S Elkotamy
Institution: Al Salam University
ORCID: 0000-0002-8449-1788
Observed ORCID: 0000-0002-8449-1788
OpenAlex ID: A5093882705
Novel imidazo[2,1-b]thiazoles and imidazo[1,2-a]pyridines tethered with indolinone motif as VEGFR-2 inhibitors and apoptotic inducers: Design, synthesis and biological evaluations
2024 · Mahmoud S. Elkotamy, Mohamed K. Elgohary, et al. · Bioorganic Chemistry · 63
Design, synthesis, and evaluation of novel benzofuran and pyrazole-based derivatives as dual AChE/BuChE inhibitors with antioxidant properties for Alzheimer's disease management
2024 · Mahmoud S. Elkotamy, Mohamed K. Elgohary, et al. · European Journal of Medicinal Chemistry · 33
Development of pyrazolo[1,5-a]pyrimidine-grafted coumarins as selective carbonic anhydrase inhibitors and tubulin polymerization inhibitors with potent anticancer activity
2025 · Mahmoud S. Elkotamy, Mohamed A. Abdelrahman, et al. · International Journal of Biological Macromolecules · 27
Fenamates and ibuprofen as foundational components in the synthesis of innovative, targeted COX-2 anti-inflammatory drugs, undergoing thorough biopharmacological assessments and in-silico computational studies
2024 · Mohamed K. Elgohary, Mahmoud S. Elkotamy, et al. · Bioorganic Chemistry · 25
Design, Synthesis and Biological Assessment of N′-(2-Oxoindolin-3-ylidene)-6-methylimidazo[2,1-b]thiazole-5-carbohydrazides as Potential Anti-Proliferative Agents toward MCF-7 Breast Cancer
2024 · Najla A. Alshaye, Mohamed K. Elgohary, et al. · Pharmaceuticals · 22
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Sulfonamide-Pyrazole derivatives as next-generation Cyclooxygenase-2 enzyme inhibitors: From molecular design to in vivo efficacy
2024 · Mohamed K. Elgohary, Mahmoud S. Elkotamy, et al. · International Journal of Biological Macromolecules · 21
Exploring antitumor activity of novel imidazo[2,1-b]thiazole and imidazo[1,2-a]pyridine derivatives on MDA-MB-231 cell line: Targeting VEGFR-2 enzyme with computational insight
2024 · Mohamed K. Elgohary, Mahmoud S. Elkotamy, et al. · Journal of Molecular Structure · 20
Design, synthesis, and molecular dynamics-driven evaluation of quinoline-sulfonamide derivatives as potent and selective EGFR inhibitors with promising anti-cancer efficacy and safety profiles
2025 · Mahmoud S. Elkotamy, Mohamed K. Elgohary, et al. · Bioorganic Chemistry · 19
Development of new LSM-83177 analogues as anti-tumor agents against colorectal cancer targeting p53-MDM2 interaction
2024 · Mohamed K. Elgohary, Mahmoud S. Elkotamy, et al. · Bioorganic Chemistry · 18
Design, Synthesis, and Biological Evaluation of Novel Phenoxy Acetic Acid Derivatives as Selective COX-2 Inhibitors Coupled with Comprehensive Bio-Pharmacological Inquiry, Histopathological Profiling, and Toxicological Scrutiny
2024 · Najla A. Alshaye, Mohamed K. Elgohary, et al. · Molecules · 16
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Discovery of enaminone-linked benzofuran derivatives as dual VEGFR-2/hCA IX inhibitors exhibiting hypoxia-mediated chemosensitization
2025 · Wagdy M. Eldehna, Zainab M. Elsayed, et al. · RSC Medicinal Chemistry · 15
Design, synthesis and biological evaluation of pyrazolo[3,4- b ]pyridine derivatives as dual CDK2/PIM1 inhibitors with potent anti-cancer activity and selectivity
2025 · Mahmoud S. Elkotamy, Mohamed K. Elgohary, et al. · Journal of Biomolecular Structure and Dynamics · 15
Molecular docking, DFT and antiproliferative properties of 4‐(3,4‐dimethoxyphenyl)−3‐(4‐methoxyphenyl)−1‐phenyl‐1H‐pyrazolo[3,4‐b]pyridine as potent anticancer agent with CDK2 and PIM1 inhibition potency
2024 · Faizah A. Binjubair, Basma S. Almansour, et al. · Drug Development Research · 14
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Spiro-fused indoline-quinazoline hybrids as smart bombs against TNF-α-mediated inflammation
2024 · Mahmoud S. Elkotamy, Mohamed K. Elgohary, et al. · International Journal of Biological Macromolecules · 13
Rationally designed Pyrazolo[1,5-a]pyrimidines as dual inhibitors of CA IX/XII and CDK6: A novel approach for NSCLC treatment
2025 · Mahmoud S. Elkotamy, Islam A. Elkelesh, et al. · European Journal of Medicinal Chemistry · 11
Development of Benzothiazole-grafted Pyrazolo[1,5-a]pyrimidines as new CDK2 inhibitors and anti-prostate cancer agents
2025 · Mahmoud S. Elkotamy, Mohamed K. Elgohary, et al. · Bioorganic Chemistry · 11
Rational Design of Triazole Hydrazide Derivatives With Imidazo[2,1‐ b ]thiazole Scaffolds as Targeted EGFR Inhibitors in NSCLC
2025 · Mohamed K. Elgohary, Mahmoud S. Elkotamy, et al. · Drug Development Research · 9
Click chemistry synthesis of triazole-grafted quinazolinones as new multi-panel anticancer agents: mechanistic insights into apoptosis and cell cycle arrest in colorectal cancer
2026 · Mohammad M. Al-Sanea, Mohamed R. Elnagar, et al. · Bioorganic Chemistry · 8
Discovering new CDK2 inhibitors by molecular docking and drug-likeness-based virtual screening for potential anticancer uses.
2024 · Mahmoud Elkotamy, Mohamed Elgohary, et al. · ERU Research Journal · 8
Discovery and characterization of phenoxyacetic acid derivatives as potential antiepileptic agents
2025 · Mohamed K. Elgohary, Mahmoud S. Elkotamy, et al. · RSC Advances · 6
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Identification of Sulfonamide‐Based Thiazolidine‐2,4‐Dione Derivatives as VEGFR‐2 and Tumor‐Associated hCA IX Inhibitors With Hypoxia‐Targeted Anti‐Colorectal Cancer Activity
2026 · Haytham O. Tawfik, Mohammed A. Dahab, et al. · Drug Development Research · 5
Pyrazole–triazole hybrids as kinase-triad inhibitors: a triple-target strategy for synergistic anticancer therapy
2026 · Mahmoud S. Elkotamy, Mohamed K. Elgohary, et al. · RSC Medicinal Chemistry · 5
2-(Piperidin-1-yl)-N-(4-sulfamoylphenyl)acetamide derivatives as novel inhibitors of cancer-associated carbonic anhydrase isoforms IX and XII
2025 · Wagdy M. Eldehna, Mostafa M. Elbadawi, et al. · International Journal of Biological Macromolecules · 5
Multi-target pyrazolopyrimidine-coumarin derivatives as potent CA IX/XII and tubulin polymerization inhibitors: Design, synthesis, and biological evaluation
2026 · Mahmoud S. Elkotamy, Mohamed A. Abdelrahman, et al. · European Journal of Medicinal Chemistry · 4
Design and evaluation of 2-(4-((2-(2-((2,6-dichloro-3-methylphenyl)amino)benzoyl)hydrazineylidene)methyl)phenoxy)acetic acid as a dual anti-inflammatory and anti-diabetic agent
2025 · Mohamed K. Elgohary, Mahmoud S. Elkotamy, et al. · Future Medicinal Chemistry · 3
Works count: 48
Citation count: 407
H-index: 13
I10-index: 16
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