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Frank Herrmann

Synthetic zinc finger repressors reduce mutant huntingtin expression in the brain of R6/2 mice
2012 · Mireia Garriga-Canut, Carmen Agustín-Pavón, et al. · Proceedings of the National Academy of Sciences · 198
Quantification Assays for Total and Polyglutamine-Expanded Huntingtin Proteins
2014 · Douglas Macdonald, Michela A. Tessari, et al. · PLoS ONE · 71
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Imaging Mutant Huntingtin Aggregates: Development of a Potential PET Ligand
2020 · Longbin Liu, Michael E. Prime, et al. · Journal of Medicinal Chemistry · 46
Meso scale discovery-based assays for the detection of aggregated huntingtin
2019 · Wolfgang Reindl, Barbara Baldo, et al. · PLoS ONE · 42
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p53 Gene Repair with Zinc Finger Nucleases Optimised by Yeast 1-Hybrid and Validated by Solexa Sequencing
2011 · Frank Herrmann, Mireia Garriga-Canut, et al. · PLoS ONE · 40
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Development of a ligand for in vivo imaging of mutant huntingtin in Huntington’s disease
2022 · Daniele Bertoglio, Jonathan Bard, et al. · Science Translational Medicine · 34
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Shedding a new light on Huntington’s disease: how blood can both propagate and ameliorate disease pathology
2020 · Marie Rieux, Melanie Alpaugh, et al. · Molecular Psychiatry · 33
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Expression of mutant exon 1 huntingtin fragments in human neural stem cells and neurons causes inclusion formation and mitochondrial dysfunction
2020 · Rhia Ghosh, Alison Wood‐Kaczmar, et al. · The FASEB Journal · 32
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Pharmacological characterization of mutant huntingtin aggregate-directed PET imaging tracer candidates
2021 · Frank Herrmann, Manuela Hessmann, et al. · Scientific Reports · 30
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A standardised frankincense extract reduces disease activity in relapsing-remitting multiple sclerosis (the SABA phase IIa trial)
2017 · Klarissa Hanja Stürner, Jan-Patrick Stellmann, et al. · Journal of Neurology Neurosurgery & Psychiatry · 30
[11C]CHDI-626, a PET Tracer Candidate for Imaging Mutant Huntingtin Aggregates with Reduced Binding to AD Pathological Proteins
2021 · Longbin Liu, Peter D. Johnson, et al. · Journal of Medicinal Chemistry · 27
Huntingtin Aggregates and Mitochondrial Pathology in Skeletal Muscle but not Heart of Late-Stage R6/2 Mice
2019 · Kerstin Kojer, Tanja Hering, et al. · Journal of Huntington s Disease · 25
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Design and Evaluation of [18F]CHDI-650 as a Positron Emission Tomography Ligand to Image Mutant Huntingtin Aggregates
2022 · Longbin Liu, Peter D. Johnson, et al. · Journal of Medicinal Chemistry · 24
Isoindolinone-Based PET Tracers for Imaging Mutant Huntingtin Aggregates
2025 · Longbin Liu, Peter D. Johnson, et al. · Journal of Medicinal Chemistry · 5
Understanding the role of the hematopoietic niche in Huntington's disease's phenotypic expression: in vivo evidence using a parabiosis model
2023 · Marie Rieux, Melanie Alpaugh, et al. · Neurobiology of Disease · 3
Correction: Shedding a new light on Huntington’s disease: how blood can both propagate and ameliorate disease pathology
2020 · Marie Rieux, Melanie Alpaugh, et al. · Molecular Psychiatry · 2
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Corrigendum to “Understanding the role of the hematopoietic niche in Huntington's disease's phenotypic expression: In vivo evidence using a parabiosis model” [Neurobiol Dis. 2023 May;180:106091. doi:10.1016/j.nbd.2023.106091. Epub 2023 Mar 24]
2023 · Marie Rieux, Melanie Alpaugh, et al. · Neurobiology of Disease · 1
High‐throughput ‘On Chip’ Protein and Nucleic Acid Transfection
2014 · Frank Herrmann, Mark Isalan · Wiley eBooks · 1
High‐throughput ‘On Chip’ Protein and Nucleic Acid Transfection
2008 · Frank Herrmann, Mark Isalan · Wiley eBooks · 1
Correction to “Isoindolinone-Based PET Tracers for Imaging Mutant Huntingtin Aggregates”
2025 · Longbin Liu, Peter D. Johnson, et al. · Journal of Medicinal Chemistry
E001 Photoaffinity probe-mediated target identification for HTT PET ligand
2024 · Kerstin Danker, Matthew Mills, et al. · Journal of Neurology Neurosurgery & Psychiatry
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D06 Quantitative assays to monitor huntingtin changes in pre-clinical and clinical hd samples
2018 · Kirsten Kuhlbrodt, Barbara Baldo, et al. · Journal of Neurology Neurosurgery & Psychiatry
B8 Ablation of p62 modulates levels of soluble and aggregated mutant huntingtin and delays end-stage disease in R6/2 mice
2016 · Kirupa Sathasivam, Casandra Gomez Paredes, et al. · Journal of Neurology Neurosurgery & Psychiatry
Works count: 23
Citation count: 645
H-index: 13
I10-index: 13
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