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Peripheral nerve decline: an underappreciated cause of injurious falls

Description: PUBLIC HEALTH RELEVANCE: This competing renewal will determine for the first time if poor sensorimotor peripheral nerve function, a novel potential risk factor, is associated with major clinical outcomes of fall injuries requiring medical care, fractures, total and fall-related Medicae utilization/expenditures, and mortality in older adults. In the initial funding period, we demonstrated that loss of sensorimotor peripheral nerve function is very common in both diabetic and non- diabetic older adults, has preventable risk factors, and is related to lower bone mineral density, muscle strength and physical performance. The ultimate goal is to determine if peripheral nerve testing identifies older adults at a higher risk for fall injuries, fractures and death that may benefit from preventive measures for nerve decline or clinical outcomes.
Funding type: research
Funder scheme: R01
Start date: 2007-09-15
End date: 2017-05-31
Investigator: ELSA S. STROTMEYER
Institution: UNIVERSITY OF PITTSBURGH AT PITTSBURGH
Funded outputs count: 484
Funder award ID: R01AG028050
OpenAlex ID: G2045259167
2026 · Mariana S. Muñoz, Natália M. Pola, et al. · Journal of Periodontology
2026 · Joel S. Burma, Caterina Rosano, et al. · Biology of Sex Differences
2026 · Lorenza Mattia, Sheena Patel, et al. · JBMR Plus · 3
2026 · Qingbo S. Wang, Jinguo Huang, et al. · iScience · 3
2026 · Greta Jianjia Cheng, Christina F. Mair, et al. · Annals of Epidemiology
2026 · Taciane Menezes da Silveira, Eleanor M. Simonsick, et al. · Oral Diseases · 2
2025 · Meghana Eswarappa, Ronit Katz, et al. · Clinical Journal of the American Society of Nephrology · 2
2025 · Amy C. Ellis, Chuong Bui, et al. · Journal of Applied Gerontology
2025 · Guoyong Ding, Jingjing Xia, et al. · CHEST Journal · 1
2025 · Sääksjärvi Katri, Härkänen Tommi, et al. · UTUPub (University of Turku)
2025 · Roelof A. J. Smit, Kaitlin H. Wade, et al. · Nature Medicine · 54
2025 · Atalie C. Thompson, Joseph Rigdon, et al. · Journal of the American Geriatrics Society · 2
2025 · Willa D. Brenowitz, Christina R. Sheppler, et al. · Journal of the American Geriatrics Society · 1
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