Transforming Exercise Testing and Physical Activity Assessment in Children: New Approaches to Advance Clinical Translational Research in Child Health
Description: A child’s participation in play and exercise is one of the most important indicators of his or her overall health and well-being. Despite the critical role played by physical activity in growth and disease prevention across the lifespan, exercise testing and physical activity assessments have failed to achieve their potential in clinical research or practice. In this project, three CTSA sites and two national organizations will work together to study novel approaches to laboratory exercise testing in healthy children and in challenging health conditions (sickle cell anemia and cystic fibrosis). The laboratory-based test results will be linked to state-of-the-art metrics of habitual physical activity, inflammation, and exercise responsive gene signals. A toolkit of innovative metrics for exercise testing will be made available to the scientific and clinical community that can transform clinical research and practice focused on exercise and its impact on children across a wide range of health and disease.
Funder: National Institutes of Health
Funding type: cooperative_agreement
Funder scheme: U01
Start date: 2018-07-17
End date: 2025-06-30
Investigator: DAN M COOPER
Institution: UNIVERSITY OF CALIFORNIA-IRVINE
Funded outputs count: 52
Funder award ID: U01TR002004
OpenAlex ID: G7419748938