Get started
Award

Systems Biology of cell Decision Processes

Amount: $228,500
Funding type: program
Funder scheme: P50
Start date: 2009-09-30
End date: 2011-09-29
Investigator: PETER KARL SORGER
Institution: MASSACHUSETTS INSTITUTE OF TECHNOLOGY
Funded outputs count: 24
Funder award ID: 3p50gm068762-07s2
OpenAlex ID: G4541497940
Biphasic JNK-Erk signaling separates the induction and maintenance of cell senescence after DNA damage induced by topoisomerase II inhibition
2023 · Tatiana S. Netterfield, Gerard J. Ostheimer, et al. · Cell Systems · 31
PDF
Biphasic JNK–Erk Signaling Separates Induction and Maintenance of Cell Senescence after DNA Damage
2022 · Tatiana S. Netterfield, Gerard J. Ostheimer, et al. · SSRN Electronic Journal
Properties of cell death models calibrated and compared using Bayesian approaches
2013 · Hoda Eydgahi, William W Chen, et al. · Molecular Systems Biology · 84
PDF
A quantitative framework For large-scale model estimation and discrimination In systems biology
2013 · Hoda Eydgahi · DSpace@MIT (Massachusetts Institute of Technology)
PDF
Site-specific conjugation of RAFT polymers to proteins via expressed protein ligation
2013 · Yan Xia, Shengchang Tang, et al. · Chemical Communications · 38
High-Affinity Manganese Coordination by Human Calprotectin Is Calcium-Dependent and Requires the Histidine-Rich Site Formed at the Dimer Interface
2012 · Joshua A. Hayden, Megan Brunjes Brophy, et al. · Journal of the American Chemical Society · 131
Conformational Control of Energy Transfer: A Mechanism for Biocompatible Nanocrystal‐Based Sensors
2012 · Euan R. Kay, Jungmin Lee, et al. · Angewandte Chemie International Edition · 38
Kinetically Controlled Nanostructure Formation in Self-Assembled Globular Protein–Polymer Diblock Copolymers
2012 · Carla S. Thomas, Liza Xu, et al. · Biomacromolecules · 62
Dual Responsiveness of a Tunable Thermosensitive Polypeptide
2012 · Caroline M. Chopko, Erika L. Lowden, et al. · ACS Macro Letters · 62
Sumoylation is tumor-suppressive and confers proliferative quiescence to hematopoietic progenitors in Drosophila melanogaster larvae
2011 · Marta E. Kalamarz, Indira Paddibhatla, et al. · Biology Open · 35
PDF
Highly Effective Gene Transfection In Vivo by Alkylated Polyethylenimine
2011 · Jennifer A. Fortune, Tatiana I. Novobrantseva, et al. · Journal of Drug Delivery · 41
PDF
Structure of the Sec13–Sec16 edge element, a template for assembly of the COPII vesicle coat
2010 · James R.R. Whittle, Thomas U. Schwartz · The Journal of Cell Biology · 104
PDF
Correction: Towards a Rigorous Assessment of Systems Biology Models: The DREAM3 Challenges
2010 · Robert J. Prill, Daniel Marbach, et al. · PLoS ONE · 85
Towards a Rigorous Assessment of Systems Biology Models: The DREAM3 Challenges
2010 · Robert J. Prill, Daniel Marbach, et al. · PLoS ONE · 439
Dynamic Fluctuations of Protein-Carbohydrate Interactions Promote Protein Aggregation
2009 · Vladimir Voynov, Naresh Chennamsetty, et al. · PLoS ONE · 42
PDF
Crystallographic and Biochemical Analysis of the Ran-binding Zinc Finger Domain
2009 · James R. Partridge, Thomas U. Schwartz · Journal of Molecular Biology · 49
The Violacein Biosynthetic Enzyme VioE Shares a Fold with Lipoprotein Transporter Proteins
2008 · Katherine S. Ryan, Carl J. Balibar, et al. · Journal of Biological Chemistry · 50
PDF
Folding and stability of the isolated Greek key domains of the long‐lived human lens proteins γD‐crystallin and γS‐crystallin
2007 · Ishara A. Mills, Shannon L. Flaugh, et al. · Protein Science · 109
PDF
Control of HslUV protease function by nucleotide binding and hydrolysis
2007 · Joseph Andrew Yakamavich · DSpace@MIT (Massachusetts Institute of Technology) · 1
PDF
Homodimerization of the G protein SRβ in the nucleotide-free state involves proline cis/trans isomerization in the switch II region
2006 · Thomas U. Schwartz, Daniel Schmidt, et al. · Proceedings of the National Academy of Sciences · 23
Mechanism of metal ion activation of the diphtheria toxin repressor DtxR
2005 · J. Alejandro D'Aquino, Jaclyn Tetenbaum-Novatt, et al. · Proceedings of the National Academy of Sciences · 57
Biochemical characterization of the chondroitinase ABC I active site
2005 · Vikas Prabhakar, Rahul Raman, et al. · Biochemical Journal · 77
PDF
Validation and refinement of gene-regulatory pathways on a network of physical interactions
2005 · Chen-Hsiang Yeang, H Craig Mak, et al. · Genome biology · 83
PDF
Chondroitinase ABC I from Proteus vulgaris: cloning, recombinant expression and active site identification
2005 · Vikas PRABHAKAR, Ishan CAPILA, et al. · Biochemical Journal · 97
PDF
Year
Topic