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DP2-GM119140

Funded outputs count: 25
Funder award ID: DP2-GM119140
OpenAlex ID: G6581751903
A genome-to-proteome map reveals how natural variants drive proteome diversity and shape fitness
2025 · Christopher M. Jakobson, Johannes Hartl, et al. · Science · 10
The Hsp90 Molecular Chaperone as a Global Modifier of the Genotype-Phenotype-Fitness Map: An Evolutionary Perspective
2024 · José Aguilar-Rodríguez, Christopher M. Jakobson, et al. · Journal of Molecular Biology · 8
Tissue-specific landscape of protein aggregation and quality control in an aging vertebrate
2024 · Yiwen R. Chen, Itamar Harel, et al. · Developmental Cell · 55
Biomolecular Condensation: A New Phase in Cancer Research
2022 · Anupam K. Chakravarty, Daniel J. McGrail, et al. · Cancer Discovery · 21
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A prion accelerates proliferation at the expense of lifespan
2021 · David M Garcia, Edgar A Campbell, et al. · eLife · 20
Protein aggregation and the evolution of stress resistance in clinical yeast
2021 · Yiwen R. Chen, Inbal Ziv, et al. · Philosophical Transactions of the Royal Society B Biological Sciences · 13
Protein self-assembly: A new frontier in cell signaling
2021 · Shady Saad, Daniel F. Jarosz · Current Opinion in Cell Biology · 17
The Hunt for Ancient Prions: Archaeal Prion-Like Domains Form Amyloid-Based Epigenetic Elements
2021 · Tomasz Zajkowski, Michael D Lee, et al. · Molecular Biology and Evolution · 29
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What Has a Century of Quantitative Genetics Taught Us About Nature's Genetic Tool Kit?
2020 · Christopher M. Jakobson, Daniel F. Jarosz · Annual Review of Genetics · 20
A Non-amyloid Prion Particle that Activates a Heritable Gene Expression Program
2019 · Anupam K. Chakravarty, Tina Smejkal, et al. · Molecular Cell · 80
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Widespread Prion-Based Control of Growth and Differentiation Strategies in Saccharomyces cerevisiae
2019 · Alan K. Itakura, Anupam K. Chakravarty, et al. · Molecular Cell · 46
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Molecular Origins of Complex Heritability in Natural Genotype-to-Phenotype Relationships
2019 · Christopher M. Jakobson, Daniel F. Jarosz · Cell Systems · 33
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Pervasive function and evidence for selection across standing genetic variation in S. cerevisiae
2019 · Christopher M. Jakobson, Richard She, et al. · Nature Communications · 18
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A Prion Epigenetic Switch Establishes an Active Chromatin State
2019 · Zachary H. Harvey, Anupam K. Chakravarty, et al. · Cell · 91
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Mutations, protein homeostasis, and epigenetic control of genome integrity
2018 · Jinglin Lucy Xie, Daniel F. Jarosz · DNA repair · 14
More than Just a Phase: Prions at the Crossroads of Epigenetic Inheritance and Evolutionary Change
2018 · Anupam K. Chakravarty, Daniel F. Jarosz · Journal of Molecular Biology · 54
It’s not magic – Hsp90 and its effects on genetic and epigenetic variation
2018 · Rebecca A. Zabinsky, Grace Alexandria Mason, et al. · Seminars in Cell and Developmental Biology · 103
It Pays To Be in Phase
2018 · Alan K. Itakura, Raymond A. Futia, et al. · Biochemistry · 38
Mapping Causal Variants with Single-Nucleotide Resolution Reveals Biochemical Drivers of Phenotypic Change
2018 · Richard She, Daniel F. Jarosz · Cell · 93
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Organizing biochemistry in space and time using prion-like self-assembly
2017 · Christopher M. Jakobson, Daniel F. Jarosz · Current Opinion in Systems Biology · 21
Protein-Based Inheritance: Epigenetics beyond the Chromosome
2017 · Zachary H. Harvey, Yiwen Chen, et al. · Molecular Cell · 183
High-throughput Screening for Protein-based Inheritance in S. cerevisiae
2017 · James S. Byers, Daniel F. Jarosz · Journal of Visualized Experiments · 2
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Comprehensive and quantitative mapping of RNA–protein interactions across a transcribed eukaryotic genome
2017 · Richard She, Anupam K. Chakravarty, et al. · Proceedings of the National Academy of Sciences · 100
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A common bacterial metabolite elicits prion-based bypass of glucose repression
2016 · David M Garcia, David Dietrich, et al. · eLife · 48
Intrinsically Disordered Proteins Drive Emergence and Inheritance of Biological Traits
2016 · Sohini Chakrabortee, James S. Byers, et al. · Cell · 208
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