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Major Depression: Stage 1 Genomewide Association in Population-Based Samples

Amount: $137,700
Funding type: research
Funder scheme: R01
Start date: 2007-09-27
End date: 2009-03-26
Investigator: PATRICK F SULLIVAN
Institution: UNIV OF NORTH CAROLINA CHAPEL HILL
Funded outputs count: 169
Funder award ID: 1r01mh081802-01
OpenAlex ID: G8670732510
Genome-wide association studies of infant and toddler temperament in European and multi-ancestry populations
2026 · Anja Hollowell, Anna Gui, et al. · Nature Human Behaviour · 3
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Genetics of major depressive disorder in a homogeneous population with uniform phenotyping
2026 · Floris Huider, Yuri Milaneschi, et al. · Molecular Psychiatry · 1
Symptom-specific genetics reveal heterogeneity within major depressive disorder
2026 · Anastasia A. Goula, Floris Huider, et al. · medRxiv
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Epigenome-wide association study of circulating interleukin-6 connects DNA methylation to immunometabolic and inflammatory health
2026 · Lucy Sinke, Jenny van Dongen, et al. · Communications Biology · 3
Genome-wide association study of major anxiety disorders in 122,341 European-ancestry cases identifies 58 loci and highlights GABAergic signaling
2026 · Nora I. Strom, Brad Verhulst, et al. · Nature Genetics · 32
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Polygenic prediction of body mass index and obesity through the life course and across ancestries
2025 · Roelof A. J. Smit, Kaitlin H. Wade, et al. · Nature Medicine · 54
Genome-wide association meta-regression identifies stem cell lineage orchestration as a key driver of acne risk
2025 · Jessye Maxwell, Brittany L. Mitchell, et al. · medRxiv
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Penetrance of Neurodevelopmental Copy Number Variants Is Associated With Variations in Cortical Morphology
2025 · Ana I. Silva, Ida E. Sønderby, et al. · Biological Psychiatry Cognitive Neuroscience and Neuroimaging · 1
Genome-wide association meta-analysis of age at onset of walking in over 70,000 infants of European ancestry
2025 · Anna Gui, Anja Hollowell, et al. · Nature Human Behaviour · 15
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Blood-Based EWAS of Asthma Polygenic Burden in The Netherlands Twin Register
2025 · Austin J. Van Asselt, René Pool, et al. · Biomolecules · 3
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Unidirectional and bidirectional causation between smoking and blood DNA methylation: evidence from twin-based Mendelian randomisation
2025 · Madhurbain Singh, Conor V. Dolan, et al. · European Journal of Epidemiology · 3
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Epigenetic signatures of asthma: a comprehensive study of DNA methylation and clinical markers
2024 · Austin J. Van Asselt, Jeffrey J. Beck, et al. · Clinical Epigenetics · 12
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Genome-wide meta-analysis of ascertainment and symptom structures of major depression in case-enriched and community cohorts
2024 · Mark J. Adams, Jackson G. Thorp, et al. · Psychological Medicine · 24
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Building machine learning prediction models for well-being using predictors from the exposome and genome in a population cohort
2024 · Dirk H. M. Pelt, Philippe C. Habets, et al. · Nature Mental Health · 17
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Genome-wide association study of major anxiety disorders in 122,341 European-ancestry cases identifies 58 loci and highlights GABAergic signaling
2024 · Nora I. Strom, Brad Verhulst, et al. · medRxiv · 27
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Breast Cancer Polygenic Risk Score Validation and Effects of Variable Imputation
2024 · Jeffrey J. Beck, John L. Slunecka, et al. · Cancers · 3
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Genome-wide association study meta-analysis of dizygotic twinning illuminates genetic regulation of female fecundity
2023 · Hamdi Mbarek, Scott D Gordon, et al. · Human Reproduction · 26
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Genome-Wide DNA Methylation Profiles in Whole-Blood and Buccal Samples—Cross-Sectional, Longitudinal, and across Platforms
2023 · Austin J. Van Asselt, Jeffrey J. Beck, et al. · International Journal of Molecular Sciences · 7
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Beyond the Global Brain Differences: Intraindividual Variability Differences in 1q21.1 Distal and 15q11.2 BP1-BP2 Deletion Carriers
2023 · Rune Boen, Tobias Kaufmann, et al. · Biological Psychiatry · 6
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Effects of smoking on genome-wide DNA methylation profiles: A study of discordant and concordant monozygotic twin pairs
2023 · Jenny van Dongen, Gonneke Willemsen, et al. · eLife · 16
Genetic Ancestry Estimates within Dutch Family Units and Across Genotyping Arrays: Insights from Empirical Analysis Using Two Estimation Methods
2023 · Jeffrey J. Beck, Talitha Ahmed, et al. · Genes
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Genetic structure of major depression symptoms across clinical and community cohorts
2023 · Mark J Adams, Jackson G Thorp, et al. · medRxiv · 4
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Longitudinal multi-omics study reveals common etiology underlying association between plasma proteome and BMI trajectories in adolescent and young adult twins
2023 · Gabin Drouard, Fiona A. Hagenbeek, et al. · medRxiv · 2
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Editor's evaluation: Effects of smoking on genome-wide DNA methylation profiles: A study of discordant and concordant monozygotic twin pairs
2022 · Melinda Aldrich · eLife
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A saturated map of common genetic variants associated with human height
2022 · Loïc Yengo, Sailaja Vedantam, et al. · Nature · 827
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