Non-invasive MRI mapping of BBB water exchange rate and permeability
Description: Project Narrative The blood-brain barrier (BBB) serves as a protective barrier for the central nervous system (CNS) by preventing the entry of harmful substances such as plasma proteins and inorganic solutes. This project is expected to result in a highly sensitive imaging tool that can detect and quantify subtle BBB dysfunction, with understanding of the underlying neurophysiological mechanisms.
Funder: National Institutes of Health
Amount: $691,100
Funding type: research
Funder scheme: R01
Start date: 2024-08-01
End date: 2029-05-31
Investigator: DANNY JJ WANG
Institution: UNIVERSITY OF SOUTHERN CALIFORNIA
Funded outputs count: 23
Funder award ID: 1r01ns134712-01a1
OpenAlex ID: G8766572272