Award

Modeling human phosphorylation networks through kinome-wide profiling

Description: PUBLIC HEALTH RELEVANCE: Protein kinases play key roles in human disease and are important targets for some anti-cancer drugs. In this research, we are using high-throughput methods to analyze the function of every human kinase. This work will help in determining which kinases will be effective drug targets, and will provide resources to assist in kinase-targeted drug discovery.
Funding type: research
Funder scheme: R01
Start date: 2013-09-10
End date: 2018-10-31
Investigator: BENJAMIN E TURK
Institution: YALE UNIVERSITY
Funded outputs count: 60
Funder award ID: R01GM104047
OpenAlex ID: G5993617699
2024 · Jung-Kuei Chen, Karl A. Merrick, et al. · Cell Reports Medicine · 44
2024 · Tomer M. Yaron-Barir, Brian A. Joughin, et al. · Nature · 152
2023 · Jung-Kuei Chen, Karl A. Merrick, et al. · bioRxiv (Cold Spring Harbor Laboratory) · 8
2023 · Jared L. Johnson, Tomer M. Yaron, et al. · Nature · 731
2022 · Tatiana S. Netterfield, Gerard J. Ostheimer, et al. · SSRN Electronic Journal
2020 · Konstantin E. Komolov, Sarah M. Sulon, et al. · Molecular Cell · 34
2020 · Daniel C. Lim, Vladimir Joukov, et al. · Molecular & Cellular Oncology · 7
2020 · Daniel C. Lim, Vladimir Joukov, et al. · Science Signaling · 32
2020 · Stanislav S. Terekhov, Yuliana A. Mokrushina, et al. · Science Advances · 24
2019 · Dajun Sang, Sudarshan Pinglay, et al. · eLife · 27
2019 · Jesse C. Patterson, Brian A. Joughin, et al. · Cell Systems · 29
2019 · Guangda Shi, Benjamin Turk · The FASEB Journal
2018 · Grace R. Jeschke, Hua Jane Lou, et al. · Journal of Biological Chemistry · 6
2018 · Pau Creixell, Jai P. Pandey, et al. · Cell Systems · 24
2018 · David Hymel, Robert A. Grant, et al. · Bioorganic & Medicinal Chemistry Letters · 17
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