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Continued optimization of the MLPCN probe ML071 into highly potent agonists of the hM1 muscarinic acetylcholine receptor

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Year: 2012
Type: article
Source: Bioorganic & Medicinal Chemistry Letters
DOI: 10.1016/j.bmcl.2012.03.088
Authors: Bruce J. Melancon, Rocco D. Gogliotti, James C. Tarr, Sam A. Saleh, Brian A. Chauder, Evan P. Lebois, Hyekyung P. Cho, Thomas J. Utley, Douglas J. Sheffler, Thomas M. Bridges, Ryan D. Morrison, J. Scott Daniels, Colleen M. Niswender, P. Jeffrey Conn, Craig W. Lindsley, Michael R. Wood
Institutions: Vanderbilt University, Vanderbilt University Medical Center
Language: English

Topic: Receptor Mechanisms and Signaling
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
SDG: Good health and well-being

Open Access status: green

Funders: Vanderbilt University, National Institutes of Health, National Institute of Mental Health
Awards: G1453181953, G2418000010, G2471675597, G2478413624, The Vanderbilt Specialized Chemistry Center for Accelerated Probe Development, G663594137, Vanderbilt NCDDDG for Discovery of Novel Treatments for Schizophrenia
OpenAlex ID: W1979142121
FWCI: 1.277
Cites: 13
Cited by: 17
Related to: 10
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