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Mitochondrial DNA mutations and aging: devils in the details?

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Year: 2008
Type: review
Source: Trends in Genetics
DOI: 10.1016/j.tig.2008.11.007
Authors: Konstantin Khrapko, Jan Vijg
Institutions: Beth Israel Deaconess Medical Center, Harvard University, Albert Einstein College of Medicine
Language: English

Topic: Mitochondrial Function and Pathology
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
SDG: Good health and well-being

Open Access status: green

Funders: Ellison Medical Foundation, United Mitochondrial Disease Foundation, National Institutes of Health, National Institute on Aging, National Institute of Neurological Disorders and Stroke
Awards: G1434137829, G3204179451, Hormonal signals, genome integrity and longevity, Oxidative Stress, alpha-Synuclein, and mtDNA Mutations in Parkinson's Disease, G7301215409, DNA Repair, Mutations and Cellular Aging, G854066850, Somatic mtDNA mutations in brain Aging: a single-cell approach
OpenAlex ID: W1996511649
FWCI: 0.707
Cites: 68
Cited by: 111
Related to: 10
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