Work

Genetic evidence of PTPN22 effects on chronic lymphocytic leukemia

Year: 2013

Type: article

Abstract: To the editor: The recent article by Negro et al represents a thorough investigation into the effect of Lyp, the gene product of PTPN22 , on BCR signaling in the pathogenesis and progression of chronic lymphocytic leukemia (CLL).[1][1] This study shows that increased Lyp enhances Akt, a serine/

Source: Blood

DOI: 10.1182/blood-2012-08-450221

Authors: Scott J. Hebbring, Susan L. Slager, Narendranath Epperla, Joseph J. Mazza, Zhan Ye, Zhiyi Zhou, Sara J. Achenbach, Daniel A. Vasco, Timothy G. Call, Kari G. Rabe, Neil E. Kay, Neil E. Caporaso, Mark C. Lanasa, Nicola J. Camp, Sara S. Strom, Lynn R. Goldin, James R. Cerhan, Murray H. Brilliant, Steven J. Schrodi

Institutions: Marshfield Clinic Research Foundation, Marshfield Clinic Research Institute, Mayo Clinic, National Cancer Institute, Division of Cancer Epidemiology and Genetics, Duke Medical Center, University of Utah, The University of Texas MD Anderson Cancer Center

Language: English

Topic: Chronic Lymphocytic Leukemia Research

Subfield: Genetics

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funders: National Institutes of Health, National Human Genome Research Institute, National Cancer Institute, U.S. National Library of Medicine, National Center for Research Resources, National Center for Advancing Translational Sciences

Awards: G2798125399, G2860569048, Molecular Epidemiology of NHL and CLL, G3709138859, Institutional Clinical and Translational Science Award (UW-Madison)(UL1), G4338327699, Genetic Epidemiology of Chronic Lymphocytic Leukemia, Molecular Pathogenesis of Monoclonal B Cell Lymphocytosis and CLL, Institutional Clinical and Translational Science Award, G8444175600

OpenAlex ID: W2056010083

FWCI: 0.74

Cites: 10

Cited by: 11

Related to: 10