Discovery and SAR of isonicotinamide BACE-1 inhibitors that bind β-secretase in a N-terminal 10s-loop down conformation
Year: 2006
Type: article
Authors: Shaun R. Stauffer, Matthew G. Stanton, Alison R. Gregro, Melissa A. Steinbeiser, Jennifer R. Shaffer, Philippe G. Nantermet, James C. Barrow, Kenneth E. Rittle, Dennis Collusi, Amy S. Espeseth, Ming-Tain Lai, Beth L. Pietrak, M. Katharine Holloway, Georgia B. McGaughey, Sanjeev K. Munshi, Jerome H. Hochman, Adam J. Simon, Harold G. Selnick, Samuel L. Graham, Joseph P. Vacca
Institution: Merck & Co., Inc., Rahway, NJ, USA (United States)
Language: English
Subfield: Physiology
Field: Medicine
Domain: Health Sciences
Open Access status: closed
OpenAlex ID: W2056257486