Work

Abstract 4481: First report of preclinical pharmacology of two novel potent AKT inhibitors and development of pharmacodynamic (PD) biomarkers in tumor and surrogate tissue

Year: 2010

Type: conference-abstract

Source: Cancer Research

DOI: 10.1158/1538-7445.am10-4481

Authors: Timothy A. Yap, Mike I. Walton, Lisa Hunter, Kyla Grimshaw, Melanie Valenti, Paul Eve, Simon P. Heaton, Lisa Pickard, John J. Caldwell, Neil Thompson, Johann S. de Bono, Stan B. Kaye, Sue A. Eccles, Paul Workman, Ian Collins, Michelle D. Garrett

Institutions: Institute of Cancer Research, Cambridge Science Centre, Cambridge Intellectual Property (United Kingdom)

Language: English

Topic: PI3K/AKT/mTOR signaling in cancer

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: closed

OpenAlex ID: W2095228707

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