Work

Label‐Free Quantitative Imaging of Cholesterol in Intact Tissues by Hyperspectral Stimulated Raman Scattering Microscopy

Year: 2013

Type: article

Abstract: A finger on the pulse: Current molecular analysis of cells and tissues routinely relies on separation, enrichment, and subsequent measurements by various assays. Now, a platform of hyperspectral stimulated Raman scattering microscopy has been developed for the fast, quantitative, and label-free imaging of biomolecules in intact tissues using spectroscopic fingerprints as the contrast mechanism.

Source: Angewandte Chemie International Edition

DOI: 10.1002/anie.201306234

Authors: Ping Wang, Junjie Li, Pu Wang, Chun‐Rui Hu, Delong Zhang, Michael Sturek, Ji‐Xin Cheng

Institutions: Purdue University West Lafayette, Indiana University School of Medicine

Language: English

Topic: Spectroscopy Techniques in Biomedical and Chemical Research

Subfield: Biophysics

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: green

Funders: National Heart, Lung, and Blood Institute, National Institute of General Medical Sciences, National Institute of Biomedical Imaging and Bioengineering

Awards: G450272272, Vibrational Photoacoustic Microscopy for Bond-selective Tissue Analysis, Exercise, Diabetes, & Coronary Smooth Muscle Ca2+

OpenAlex ID: W2098442298

FWCI: 5.884

Cites: 56

Cited by: 109

Related to: 10