Work

High Frequency of False-Positive Hepatitis C Virus Enzyme-Linked Immunosorbent Assay in Rakai, Uganda

Year: 2013

Type: article

Study design: Observational Study

Abstract: The prevalence of hepatitis C virus (HCV) infection in sub-Saharan Africa remains unclear. We tested 1000 individuals from Rakai, Uganda, with the Ortho version 3.0 HCV enzyme-linked immunosorbent assay. All serologically positive samples were tested for HCV RNA. Seventy-six of the 1000 (7.6%) participants were HCV antibody positive; none were confirmed by detection of HCV RNA.

Source: Clinical Infectious Diseases

DOI: 10.1093/cid/cit602

Authors: C. E. Mullis, O. Laeyendecker, S. J. Reynolds, P. Ocama, J. Quinn, I. Boaz, R. H. Gray, G. D. Kirk, D. L. Thomas, T. C. Quinn, L. Stabinski

Institutions: Johns Hopkins University, National Institutes of Health, National Institute of Allergy and Infectious Diseases, Makerere University, Rakai Health Sciences Program

Language: English

Topic: Hepatitis C virus research

Subfield: Hepatology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $4,763

Funders: National Institutes of Health, National Institute on Drug Abuse, National Institute of Allergy and Infectious Diseases

Awards: G33067752, HIV HCV Coinfection Antiviral Therapy and Fibrosis, AIDS Linked to the IntraVenous Experience (ALIVE) Study, LC: HIV PREVENTION TRIALS NETWORK, G95938990

OpenAlex ID: W2138568618

FWCI: 3.847

Cites: 11

Cited by: 65

Related to: 10