Intake estimation of total and individual flavan-3-ols, proanthocyanidins and theaflavins, their food sources and determinants in the European Prospective Investigation into Cancer and Nutrition (EPIC) study
Year: 2011
Type: article
Abstract: Epidemiological studies suggest health-protective effects of flavan-3-ols and their derived compounds on chronic diseases. The present study aimed to estimate dietary flavan-3-ol, proanthocyanidin (PA) and theaflavin intakes, their food sources and potential determinants in the European Prospective Investigation into Cancer and Nutrition (EPIC) calibration cohort. Dietary data were collected using a standardised 24 h dietary recall software administered to 36 037 subjects aged 35-74 years. Dietary data were linked with a flavanoid food composition database compiled from the latest US Department of Agriculture and Phenol-Explorer databases and expanded to include recipes, estimations and retention factors. Total flavan-3-ol intake was the highest in UK Health-conscious men (453·6 mg/d) and women of UK General population (377·6 mg/d), while the intake was the lowest in Greece (men: 160·5 mg/d; women: 124·8 mg/d). Monomer intake was the highest in UK General population (men: 213·5 mg/d; women: 178·6 mg/d) and the lowest in Greece (men: 26·6 mg/d in men; women: 20·7 mg/d). Theaflavin intake was the highest in UK General population (men: 29·3 mg/d; women: 25·3 mg/d) and close to zero in Greece and Spain. PA intake was the highest in Asturias (men: 455·2 mg/d) and San Sebastian (women: 253 mg/d), while being the lowest in Greece (men: 134·6 mg/d; women: 101·0 mg/d). Except for the UK, non-citrus fruits (apples/pears) were the highest contributors to the total flavan-3-ol intake. Tea was the main contributor of total flavan-3-ols in the UK. Flavan-3-ol, PA and theaflavin intakes were significantly different among all assessed groups. This study showed heterogeneity in flavan-3-ol, PA and theaflavin intake throughout the EPIC countries.
Source: British Journal Of Nutrition
Authors: Viktoria Knaze, Raul Zamora-Ros, Leila Luján-Barroso, Isabelle Romieu, Augustin Scalbert, Nadia Slimani, Elio Riboli, Caroline T. M. van Rossum, H. Bas Bueno-de-Mesquita, Antonia Trichopoulou, Vardis Dilis, Konstantinos Tsiotas, Guri Skeie, Dagrun Engeset, J. Ramón Quirós, Esther Molina, José María Huerta, Francesca Crowe, Elisabet Wirfäl, Ulrika Ericson, Petra H. M. Peeters, Rudolf Kaaks, Birgit Teucher, Gerd Johansson, Ingegerd Johansson, Rosario Tumino, Heiner Boeing, Dagmar Drogan, Pilar Amiano, Amalia Mattiello, Kay-Tee Khaw, Robert Luben, Vittorio Krogh, Eva Ardanáz, Carlotta Sacerdote, Simonetta Salvini, Kim Overvad, Anne Tjønneland, Anja Olsen, Marie-Christine Boutron-Ruault, Guy Fagherazzi, Florence Perquier, Carlos A. González
Institutions: Institut d'Investigació Biomédica de Bellvitge, Institut Català d'Oncologia, Centre international de recherche sur le cancer, Imperial College London, National Institute for Public Health and the Environment, University Medical Center Utrecht, National and Kapodistrian University of Athens, Hellenic Health Foundation, UiT The Arctic University of Norway, Gobierno del Principado de Asturias, Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública, Andalusian School of Public Health, University of Oxford, Lund University, German Cancer Research Center, Umeå University, Azienda Usl 8 Arezzo, German Institute of Human Nutrition, Basque Government, Biogipuzkoa Health Research Institute, Federico II University Hospital, University of Naples Federico II, University of Cambridge, Fondazione IRCCS Istituto Nazionale dei Tumori, Italian institute for Genomic Medicine, Piedmont Reference Center for Epidemiology and Cancer Prevention, Istituto per lo Studio e la Prevenzione Oncologica, Aarhus University, Danish Cancer Society, Inserm, Institut Gustave Roussy, Centre de recherche en Epidémiologie et Santé des Populations
Language: English
Subfield: Biochemistry
Field: Medicine
Domain: Health Sciences
Open Access status: bronze
Funders: Compagnia di San Paolo, Wellcome Trust, Cancer Research UK, British Heart Foundation, Stroke Association, European Commission, Institut National de la Santé et de la Recherche Médicale, Bundesministerium für Bildung und Forschung, Ligue Contre le Cancer, Stavros Niarchos Foundation, Deutsche Krebshilfe, Institut Gustave-Roussy, Hellenic Health Foundation, Medical Research Council
Award: G5897142711
OpenAlex ID: W2148841223