Work

Bone marrow transplantation prevents right ventricle disease in the caveolin-1–deficient mouse model of pulmonary hypertension

Year: 2017

Type: article

Abstract: KO with WT BM prevented spontaneous development of PH, including elevation of RVSP and maladaptive RV hypertrophy, but not pulmonary endothelial remodeling. Healthy BM has a protective role in the right ventricle independent of pulmonary vascular disease.

Source: Blood Advances

DOI: 10.1182/bloodadvances.2016002691

Authors: Kewal Asosingh, Nicholas Wanner, Kelly Weiss, Kimberly Queisser, Liya Gebreab, Biruk Kassa, Eric Stuehr, Brian Graham, Serpil Erzurum

Institutions: Cleveland Clinic, Cleveland Clinic Research, University of Colorado Anschutz, University of Colorado Denver

Language: English

Topic: Pulmonary Hypertension Research and Treatments

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,800

Funders: University of Pittsburgh, National Institutes of Health, National Heart, Lung, and Blood Institute

Awards: G1912839633, G231556210, Pulmonary Vascular-Right Ventricular Axis Research Program, Role of Th2 CD4 T Cells in Schistosoma Pulmonary Hypertension, Airway redox biochemistry as a deteriminant of asthma phenotype during adolescen*, Nitric Oxide in Pulmonary Hypertension, Nitric Oxide in Pulmonary Hypertension, G9000176715, Activation, Phenotype and Function of CD4 T Cells in Schistosoma-Pulmonary Hypertension

OpenAlex ID: W2596139951

FWCI: 1.357

Cites: 40

Cited by: 13

Related to: 10