Work

Slow Intrathecal Injection of rAAVrh10 Enhances its Transduction of Spinal Cord and Therapeutic Efficacy in a Mutant SOD1 Model of ALS

Year: 2017

Type: article

Source: Neuroscience

DOI: 10.1016/j.neuroscience.2017.10.001

Authors: Dongxiao Li, Chong Liu, Chunxing Yang, Dan Wang, Dongxia Wu, Yinkuang Qi, Qin Su, Guangping Gao, Zuoshang Xu, Yansu Guo

Institutions: Second Hospital of Hebei Medical University, University of Massachusetts Chan Medical School, Hebei Medical University

Language: German

Topic: Virus-based gene therapy research

Subfield: Genetics

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funders: Hebei Provincial Department of Human Resources and Social Security, Natural Science Foundation of Hebei Province, National Institutes of Health, National Heart, Lung, and Blood Institute, National Institute of Allergy and Infectious Diseases, National Institute of Neurological Disorders and Stroke

Awards: New Approaches to Gene Therapy for Alpha-1 Antitrypsin Deficiency, A new approach to modeling ALS based on TBK1 mutation in mice, G4826372969, A Gene therapeutic approach to stable suppression of HIV-1 replication, An in vivo approach to understanding mutant PFN1 toxicity on motor neurons, Oligodendrocyte-focused rAAV gene therapy strategies for Canavan disease and Leukodystrophies

OpenAlex ID: W2761044458

FWCI: 1.95

Cites: 22

Cited by: 27

Related to: 10