Work

The Augmented R-Loop Is a Unifying Mechanism for Myelodysplastic Syndromes Induced by High-Risk Splicing Factor Mutations

Year: 2018

Type: article

Source: Molecular Cell

DOI: 10.1016/j.molcel.2017.12.029

Authors: Liang Chen, Jia-Yu Chen, Yi-Jou Huang, Ying Gu, Jinsong Qiu, Hao Qian, Changwei Shao, Xuan Zhang, Jing Hu, Hairi Li, Shunmin He, Yu Zhou, Omar Abdel-Wahab, Dong-Er Zhang, Xiang-Dong Fu

Institutions: University of California San Diego, Moores Cancer Center, Chinese Academy of Sciences, Institute of Zoology, Key Laboratory of Zoological Systematics and Evolution, Wuhan University, Memorial Sloan Kettering Cancer Center

Language: English

Topic: RNA Research and Splicing

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: bronze

Funders: National Institutes of Health, University of California, San Diego, National Key Research and Development Program of China, National Human Genome Research Institute, National Cancer Institute, National Institute of General Medical Sciences, National Institute of Diabetes and Digestive and Kidney Diseases

Awards: G1763612369, Regulation of RNA metabolism and cell growth control by SR protein kinases, Synergestic roles of SRF2 and RUNX1 in blood cell development and pathology, Function and regulation of the human splicing factor SC35, Functional RNA elements in the human genome, G720370105, Synergestic roles of SRF2 and RUNX1 in blood cell development and pathology, G9000308843, Cancer Center Support Grant

OpenAlex ID: W2786842416

FWCI: 10.76

Cites: 60

Cited by: 299

Related to: 10