Genome-wide analyses identify 68 new loci associated with intraocular pressure and improve risk prediction for primary open-angle glaucoma
Year: 2018
Type: review
Study design: Observational Study
Source: Nature Genetics
Institutions: Moorfields Eye Hospital NHS Foundation Trust, University of Cambridge, NIHR Moorfields Biomedical Research Centre, University College London, Case Western Reserve University, MRC Epidemiology Unit, St Thomas' Hospital, King's College London, Johns Hopkins University, Johns Hopkins Hospital, National University of Singapore, Singapore National Eye Center, Singapore Eye Research Institute, Duke-NUS Medical School, National University Health System, Massachusetts Eye and Ear Infirmary, Harvard University
Language: English
Subfield: Ophthalmology
Field: Medicine
Domain: Health Sciences
Open Access status: green
Funders: Donald W. Reynolds Foundation, Research to Prevent Blindness, Amgen, Wellcome Trust, Broad Institute, Cancer Research UK, National Institute for Health and Care Research, British Heart Foundation, Diabetes UK, King's College London, Fondation Leducq, Northwest Regional Development Agency, Moorfields Eye Hospital NHS Foundation Trust, Moorfields Eye Charity, National Institutes of Health, Medical Research Council, National Heart, Lung, and Blood Institute, National Human Genome Research Institute, National Eye Institute, National Cancer Institute, National Center for Research Resources, National Center for Advancing Translational Sciences
Awards: COBRE in Sensory Neuroscience, Women's Health Study: Continued Follow-Up, Whole Genome Association Study of Mammographic Density, Linkage Study of Juvenile Glaucoma, G1214533002, Diagnostic Innovations in Glaucoma Study: Visual Function, G151562090, G1528515809, High Throughput Science - Investigating the genetic determinants of healthy ageing: the MRC EPIC-Norfolk study, G208087735, G229684361, G2332775, Long Noncoding RNA lncLOXL1 and Exfoliation Syndrome., Molecular Genetics of Primary Open-angle Glaucoma, G2552864338, Genetics and Functional Studies of Age-Related Macular Degeneration, Biochemical Markers in the nurses' Health Study Cohort, G2750880407, Admixture Mapping of Glaucoma Genes in African Americans, The epidemiology of glaucoma., Gene-Environment Interactions in Glaucoma, G3219722387, Clinical PhD Programme at the University of Cambridge., G385201875, G3964026636, Dietary and Hormonal Determinants of Cancer in Women, NIHR Senior Investigator Award, G4025249204, G4102267556, Genetic Etiologies of Primary Open Angle Glaucoma, Genes and Environment Initiative in Glaucoma, G4376790518, G4409035895, Genome Wide Association Coordinating Center, G459566519, Genomic Architecture of Progression and Treatment Response in AMD, Whole-genome Association Analyses of Refractive Error and Myopia in the UK Biobank Study, G4852347705, G5121713029, A Center for GEI Association Studies, G518464440, Comparative Approach to Genomics of Complex Traits, G5315906942, Diagnostic Innovations in Glaucoma: Structural Assessment, G558986044, Molecular Genetics of Norma Tension Glaucoma, Genome-Wide Study of Cataract and Low HDL in the Personalized Medicine Research P, G5850737185, G6008908520, G6025337639, G6035964259, GENECARD-Gene Identification in Early-Onset CAD, Molecular Genetics of Primary Open-angle Glaucoma, Institutional Clinical and Translational Science Award, G6594529311, TRIAL OF ASPIRIN AND VITAMIN E IN WOMEN, G6957823285, Genomic Convergence in Primary Open Angle Glaucoma, G7145200261, UNIFYING GENETICS EPIDEMIOLOGY OF MACULAR DEGENERATION, Long Term Multidisciplinary Study of Cancer in Women: The Nurses Health Study, Expression Profile Approach to Glaucoma Gene Detection, Biochemical Markers in the Nurses? Health Study Cohort, Women's Health Study: Continued Follow-up, Cancer Epidemiology Cohort in Male Health Professionals, G7962241407, G801047195, Candidate Genes for Primary Open Angle Glaucoma, FAMILIAL PRIMARY OPEN ANGLE GLAUCOMA, IRIS: Incorporating Research Into Sight, NIHR Senior Investigator Award, G9000028950, G9000043482, G9000058182, G9000087432, G9000190097, G9000207239, P30 Core Grant for Vision Research, University of Wisconsin Institute for Clinical and Translational Research, NEIGHBORHOOD Consortium for POAG Genetics, Novel Glaucoma Diagnostics for Structure and Function., Diurnal Intraocular Pressure Variability Assessment
OpenAlex ID: W2803323905