Work

Perturb-Seq: Dissecting Molecular Circuits with Scalable Single-Cell RNA Profiling of Pooled Genetic Screens

Year: 2016

Type: article

Source: Cell

DOI: 10.1016/j.cell.2016.11.038

Authors: Atray Dixit, Oren Parnas, Biyu Li, Jenny Chen, Charles P. Fulco, Livnat Jerby-Arnon, Nemanja D. Marjanovic, Danielle Dionne, Tyler Burks, Raktima Raychowdhury, Britt Adamson, Thomas M. Norman, Eric S. Lander, Jonathan S. Weissman, Nir Friedman, Aviv Regev

Institutions: Broad Institute, Harvard–MIT Division of Health Sciences and Technology, Harvard University, Massachusetts Institute of Technology, QB3, University of California, San Francisco, Howard Hughes Medical Institute, Hebrew University of Jerusalem

Language: English

Topic: Single-cell and spatial transcriptomics

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: bronze

Funders: Howard Hughes Medical Institute, National Institutes of Health, Klarman Cell Observatory, Broad Institute, National Institute on Aging, National Institute on Drug Abuse, National Human Genome Research Institute, National Cancer Institute

Awards: Center for Cell Circuits, G4186406324, G496907445, Center for Cell Circuits, Human Gene Knockdowns that May Extend Lifespan, Harnessing CRISPR for Targeted and Inducible Epigenomic Reprogramming, Cancer Center Support (Core) Grant

OpenAlex ID: W2561754210

FWCI: 55.46

Cites: 64

Cited by: 1,863

Related to: 10