Work

Pharmacophore-based design of novel 3-hydroxypyrimidine-2,4-dione subtypes as inhibitors of HIV reverse transcriptase-associated RNase H: Tolerance of a nonflexible linker

Year: 2019

Type: article

Source: European Journal of Medicinal Chemistry

DOI: 10.1016/j.ejmech.2019.01.081

Authors: Jing Tang, Ha T. Do, Andrew D. Huber, Mary C. Casey, Karen A. Kirby, Daniel J. Wilson, Jayakanth Kankanala, Michael A. Parniak, Stefan G. Sarafianos, Zhengqiang Wang

Institutions: University of Minnesota, University of Missouri, Emory University, University of Pittsburgh

Language: English

Topic: HIV/AIDS drug development and treatment

Subfield: Infectious Diseases

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funders: National Institutes of Health, Center for Drug Design, University of Minnesota, National Institute of Allergy and Infectious Diseases

Awards: Novel antivirals targeting the RNase H activity of HIV reverse transcriptase, Behavior of HIV in Viral Environments (B-HIVE)

OpenAlex ID: W2912744716

FWCI: 3.831

Cites: 53

Cited by: 27

Related to: 10