Work

3'-Tetrahydrofuranylglycine as a novel, unnatural amino acid surrogate for asparagine in the design of inhibitors of the HIV protease

Year: 1993

Type: article

Abstract: This property may result in reduced susceptibility to resistance since these represent the genetically most divergent strains of HIV presently known to exist.

Source: Journal of the American Chemical Society

DOI: 10.1021/ja00055a069

Authors: Wayne J. Thompson, Arun K. Ghosh, M. Katharine Holloway, Hee Yoon Lee, Peter M. Munson, John E. Schwering, Jenny Wai, Paul L. Darke, Joan Zugay

Language: English

Topic: HIV/AIDS drug development and treatment

Subfield: Infectious Diseases

Field: Medicine

Domain: Health Sciences

Open Access status: green

Funders: National Institute of General Medical Sciences, Division of Chemistry

Award: DESIGN AND SYNTHESIS OF NONPEPTIDE PROTEASE INHIBITORS

OpenAlex ID: W2952067065

FWCI: 6.124

Cites: 12

Cited by: 42

Related to: 10