Work

CRISPR-Based Therapeutic Genome Editing: Strategies and In Vivo Delivery by AAV Vectors

Year: 2020

Type: review

Source: Cell

DOI: 10.1016/j.cell.2020.03.023

Authors: Dan Wang, Feng Zhang, Guangping Gao

Institutions: University of Massachusetts Chan Medical School, Broad Institute, Howard Hughes Medical Institute, McGovern Institute for Brain Research, Massachusetts Institute of Technology

Language: English

Topic: CRISPR and Genetic Engineering

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: bronze

Funders: Howard Hughes Medical Institute, Cystic Fibrosis Foundation, Michelson Prize and Grants, Massachusetts Institute of Technology, Pitt Hopkins Research Foundation, G. Harold and Leila Y. Mathers Foundation, Grace Science Foundation, Edward Mallinckrodt, Jr. Foundation, National Institutes of Health, National Heart, Lung, and Blood Institute, National Institute of Mental Health, National Human Genome Research Institute, National Institute of Neurological Disorders and Stroke

Awards: Advancing programmable RNA-targeting tools for research and therapeutics, New Approaches to Gene Therapy for Alpha-1 Antitrypsin Deficiency, G3726326847, Center for Cell Circuits, G4186406324, Next Generation of Recombinant AAV Serotype For Gene Therapy, Massively-parallel functional interrogation of psychiatric genetics, Exploration of Diverse Mobile Genetic Elements for Precision Genome Manipulation, Develop combinatorial non-viral and viral CRISPR delivery for lung diseases, G9000129365, Oligodendrocyte-focused rAAV gene therapy strategies for Canavan disease and Leukodystrophies

OpenAlex ID: W3015141182

FWCI: 6.587

Cites: 175

Cited by: 526

Related to: 10