Work

A general chemical principle for creating closure-stabilizing integrin inhibitors

Year: 2022

Type: article

Source: Cell

DOI: 10.1016/j.cell.2022.08.008

Authors: Fu-Yang Lin, Jing Li, Yonghua Xie, Jianghai Zhu, Thi Thu Huong Nguyen, Yonghui Zhang, Jieqing Zhu, Timothy A. Springer

Institutions: Boston Children's Hospital, Harvard University, Tsinghua University, Medical College of Wisconsin, Versiti Blood Center of Wisconsin

Language: English

Topic: Cell Adhesion Molecules Research

Subfield: Immunology and Allergy

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: bronze

Funders: National Heart, Lung, and Blood Institute, National Institute of General Medical Sciences

Awards: Activation trajectories of integrin Î±5Î²1, Structural Mechanisms Underlying the Activity Regulation of the Receptor-like Protein Tyrosine Phosphatase, CD148/PTPRJ, Structural Transition of Cellular Integrins and Applications Thereof

OpenAlex ID: W4295959779

FWCI: 9.329

Cites: 87

Cited by: 60

Related to: 10