Work

Small molecule drugs promote repopulation of transplanted hepatocytes by stimulating cell dedifferentiation

Year: 2023

Type: article

Abstract: Background & Aims: and find a way to promote the growth of transplanted hepatocytes. Methods: effects of these compounds on transplanted hepatocytes were then evaluated. Results: , by facilitating HPC conversion. Conclusions: and may facilitate the application of hepatocyte therapy. Impact and implications: and may facilitate the application of hepatocyte therapy.

Source: JHEP Reports

DOI: 10.1016/j.jhepr.2023.100670

Authors: Mengmeng Jiang, Ren Guo, Yan Ai, Gang Wang, Peilan Tang, Xiaohui Jia, Bingqing He, Qianting Yuan, Xin Xie

Institutions: Chinese Academy of Sciences, ShanghaiTech University, Shanghai Institute of Materia Medica, National Center for Drug Screening, University of Chinese Academy of Sciences, Fudan University, Nanchang University, State Key Laboratory of Drug Research

Language: English

Topic: Liver physiology and pathology

Subfield: Hepatology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,900

Funders: National Natural Science Foundation of China, Chinese Academy of Sciences, Ministry of Science and Technology of the People's Republic of China, China Postdoctoral Science Foundation, National Key Research and Development Program of China

Awards: G1683011822, G2018211022, G2035403985, G2986465039, G2992754588, G5441179078, 中链脂肪酸受体作为抗炎症性肠病药物作用新靶点的研究

OpenAlex ID: W4316019742

FWCI: 1.653

Cites: 40

Cited by: 13

Related to: 10