Work

Rational design of a miniprotein to inhibit the oncogenic transcription factor MYC

Year: 2024

Type: conference-abstract

Abstract: Loop-DNA backbone interaction Stabilization of DNA binding domain vector (hydrophobic core and H-bond) 1 µM DuoMYC-F 4 hours 1 µM DuoMYC-F 24 hours 1 µM Omomyc-F 24 hours 1 µM Omomyc-F 4 hours FITC Merge CONCLUSION

Source: European Peptide Symposium (EPS)

DOI: 10.17952/37eps.2024.p1094

Authors: B. Ellenbroek, J. Kahler, D. Arella, C. Lin, W. Jespers, S. Pomplun

Language: English

Topic: Protein Structure and Dynamics

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: bronze

OpenAlex ID: W4403190788

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