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Synthesis and Evaluation of Optical Properties, SHP2 Inhibitory Activity, and Cellular Imaging for Novel 2-Quinolone Derivatives

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Year: 2025
Type: article
Source: Anti-Cancer Agents in Medicinal Chemistry
DOI: 10.2174/0118715206337347250219112715
Authors: Chun Zhang, Yuting Yang, Li-Xin Gao, Suya Gan, Jia Li, Xin Wang, Xin Wang, Yu-Bo Zhou, Yu-Bo Zhou, Wen-Long Wang
Institutions: Jiangnan University, Chinese Academy of Sciences, Shanghai Institute of Materia Medica, National Center for Drug Screening, State Key Laboratory of Drug Research, Henan University
Language: English

Topic: Protein Tyrosine Phosphatases
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
SDG: Good health and well-being

Open Access status: closed

Funders: National Natural Science Foundation of China, Fundamental Research Funds for the Central Universities
Awards: G4614633758, E76K突变型蛋白酪氨酸磷酸酶SHP2变构抑制剂的设计、连续化合成及抗髓系白血病活性研究, G6442106538
OpenAlex ID: W4408635049
FWCI:
Cites: 42
Cited by:
Related to: 10
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