Work

Discovery of Novel Tridentate Alkenyl Diacid Derivatives as Potent ATP Citrate Lyase Inhibitors for the Treatment of Hepatocellular Carcinoma

Year: 2025

Type: article

Source: Journal of Medicinal Chemistry

DOI: 10.1021/acs.jmedchem.5c00480

Authors: Yurou Yang, Jimao Zhai, Fan Wang, Gaolei Song, Honghong Xu, Xinyu Sun, Qingbo Zhang, Jie Ma, Min Gu, Yinglei Gao, Mei Zhang, Jian Ding, Yi Chen, Jingya Li, Zhifu Xie, Yanfen Fang, Fajun Nan

Institutions: Chinese Academy of Sciences, Shanghai Institute of Materia Medica, National Center for Drug Screening, University of Chinese Academy of Sciences, State Key Laboratory of Drug Research, Nanjing University of Chinese Medicine

Language: English

Topic: Cancer, Lipids, and Metabolism

Subfield: Cancer Research

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: closed

Funders: Program of Shanghai Academic Research Leader, Shanghai Institute of Materia Medica, Chinese Academy of Sciences

Awards: G270004384, G6390070855

OpenAlex ID: W4412487927

FWCI: 0.978

Cites: 27

Cited by: 3

Related to: 10