Design of Novel Exatecan-Amide Linker-Payloads for the Development of Stable, Low-Aggregating, and Highly Efficacious Antibody-Drug Conjugates
Year: 2026
Type: article
Source: Journal of Medicinal Chemistry
Authors: Ryan V. Quiroz, Simon B. Lang, Rebecca E. Johnson, Nancy Zepeda, Vlad Bacauanu, Christian L. Morales, Manoj Charati, John A. Flygare, Olivia R. Chastain, Zhong L. Hua, Edward P. Bowman, Bernhard H. Geierstanger, Alycia K. Uyeoka, Fan Zhang, Huimin Zhong, Esther Kofman, Daniela M. Tomazela, Laurence Fayadat-Dilman, Mengxuan Jia, Michael Judo, Ian Knemeyer, Peyman Akbari, Qingyun Yan, Evan R. Barry, Alan B. Northrup, W. Michael Seganish
Institution: Merck & Co., Inc., Rahway, NJ, USA (United States)
Language: English
Subfield: Radiology, Nuclear Medicine and Imaging
Field: Medicine
Domain: Health Sciences
Open Access status: closed
Funder: Merck
OpenAlex ID: W7158581566