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Eric Haines
Observed name:
Haines, Eric
Observed institutions:
Royal Victoria Hospital,
EMD Serono, Inc. (United States),
Dana-Farber Cancer Institute,
Merck Healthcare KGaA, Darmstadt (Germany),
McGill University,
Université de Montréal
show all 6
ORCID:
0000-0002-9078-0156
Observed ORCID:
0000-0002-9078-0156
OpenAlex ID:
A5017553205
CDK4/6 Inhibition Augments Antitumor Immunity by Enhancing T-cell Activation
2017
·
Jiehui Deng
, Eric S. Wang
, et al.
·
Cancer Discovery
·
778
BT8009; A Nectin-4 Targeting Bicycle Toxin Conjugate for Treatment of Solid Tumors
2022
·
Michael Rigby
, Gavin Bennett
, et al.
·
Molecular Cancer Therapeutics
·
85
Smad Signaling Antagonizes STAT5-mediated Gene Transcription and Mammary Epithelial Cell Differentiation
2007
·
Eftihia Cocolakis
, Meiou Dai
, et al.
·
Journal of Biological Chemistry
·
60
Palbociclib resistance confers dependence on an FGFR-MAP kinase-mTOR-driven pathway inKRAS-mutant non-small cell lung cancer
2018
·
Eric Haines
, Ting Chen
, et al.
·
Oncotarget
·
54
PDF
The Adaptor Proteins p66Shc and Grb2 Regulate the Activation of the GTPases ARF1 and ARF6 in Invasive Breast Cancer Cells
2014
·
Eric Haines
, Caroline Saucier
, et al.
·
Journal of Biological Chemistry
·
51
Tyrosine Phosphorylation of Grb2: Role in Prolactin/Epidermal Growth Factor Cross Talk in Mammary Epithelial Cell Growth and Differentiation
2009
·
Eric Haines
, Parham Minoo
, et al.
·
Molecular and Cellular Biology
·
44
BT7480, a novel fully synthetic Bicycle tumor-targeted immune cell agonist™ (Bicycle TICA™) induces tumor localized CD137 agonism
2021
·
Kristen Hurov
, Johanna Lahdenranta
, et al.
·
Journal for ImmunoTherapy of Cancer
·
39
PDF
DNA-PK inhibitor peposertib enhances p53-dependent cytotoxicity of DNA double-strand break inducing therapy in acute leukemia
2021
·
Eric Haines
, Yuki Nishida
, et al.
·
Scientific Reports
·
37
PDF
Anticancer immunity induced by a synthetic tumor-targeted CD137 agonist
2021
·
Punit Upadhyaya
, Johanna Lahdenranta
, et al.
·
Journal for ImmunoTherapy of Cancer
·
32
PDF
The small GTPase ADP-Ribosylation Factor 1 mediates the sensitivity of triple negative breast cancer cells to EGFR tyrosine kinase inhibitors
2015
·
Eric Haines
, Sabrina Schlienger
, et al.
·
Cancer Biology & Therapy
·
25
PDF
Abstract C061: BT8009, a Bicycle Toxin Conjugate targeting Nectin-4, shows target selectivity, and efficacy in preclinical large and small tumor models
2019
·
Michael Rigby
, Gavin Bennett
, et al.
·
Molecular Cancer Therapeutics
·
9
The MEK–RAF molecular glue IK-595 has potent antitumor activity across RAS/MAPK pathway-altered cancers
2026
·
Eric Haines
, Michael Burke
, et al.
·
Nature Cancer
·
5
706 BT7480, a fully synthetic tumor-targeted immune cell agonist (TICA™) induces tumor localized CD137 agonism and modulation of tumor immune microenvironment
2020
·
Punit Upadhyaya
, Kristen Hurov
, et al.
·
Journal for ImmunoTherapy of Cancer
·
3
Abstract 4830: Selective DNA-PK inhibitor, M3814, boosts p53 apoptotic response to DNA double strand breaks and effectively kills acute leukemia cells: Implications for AML therapy
2018
·
Eric Haines
, Astrid Zimmermann
, et al.
·
Cancer Research
·
2
789 Generation of a Bicycle NK-TICA™, a novel NK cell engaging molecule to enhance targeted tumor cytotoxicity
2021
·
Fay Dufort
, Christopher Leitheiser
, et al.
·
Journal for ImmunoTherapy of Cancer
·
1
PDF
Abstract 1728: Nectin-4-dependent immune cell stimulation and anti-tumor efficacy by BT7480, a Nectin-4/CD137 Bicycle®tumor-targeted immune cell agonist (TICA™)
2021
·
Kristen Hurov
, Johanna Lahdenranta
, et al.
·
Cancer Research
·
1
Correction: Smad signaling antagonizes STAT5-mediated gene transcription and mammary epithelial cell differentiation
2023
·
Eftihia Cocolakis
, Meiou Dai
, et al.
·
Journal of Biological Chemistry
PDF
Supplementary Data from BT8009; A Nectin-4 Targeting Bicycle Toxin Conjugate for Treatment of Solid Tumors
2023
·
Michael Rigby
, Gavin Bennett
, et al.
PDF
Supplementary Data from BT8009; A Nectin-4 Targeting Bicycle Toxin Conjugate for Treatment of Solid Tumors
2023
·
Michael Rigby
, Gavin Bennett
, et al.
PDF
Supplementary Figure from BT8009; A Nectin-4 Targeting Bicycle Toxin Conjugate for Treatment of Solid Tumors
2023
·
Michael Rigby
, Gavin Bennett
, et al.
PDF
Supplementary Figure from BT8009; A Nectin-4 Targeting Bicycle Toxin Conjugate for Treatment of Solid Tumors
2023
·
Michael Rigby
, Gavin Bennett
, et al.
Supplementary Data from BT8009; A Nectin-4 Targeting Bicycle Toxin Conjugate for Treatment of Solid Tumors
2023
·
Michael Rigby
, Gavin Bennett
, et al.
Data from BT8009; A Nectin-4 Targeting Bicycle Toxin Conjugate for Treatment of Solid Tumors
2023
·
Michael Rigby
, Gavin Bennett
, et al.
Data from BT8009; A Nectin-4 Targeting Bicycle Toxin Conjugate for Treatment of Solid Tumors
2023
·
Michael Rigby
, Gavin Bennett
, et al.
Abstract 1724: Microinjection of Nectin-4/CD137 tumor-targeted immune cell agonist (TICA™) activates the local tumor microenvironment
2021
·
Johanna Lahdenranta
, Stephen J. Blakemore
, et al.
·
Cancer Research
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Works count:
30
Citation count:
1,226
H-index:
10
I10-index:
10
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