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Gaku Oshikawa
Observed names:
G Oshikawa,
G. Oshikawa,
GAKU OSHIKAWA
Institution:
Musashino Red Cross Hospital
Observed institutions:
Tokyo Medical and Dental University,
Tokyo Metropolitan Komagome Hospital,
Musashino Red Cross Hospital
OpenAlex ID:
A5032874540
FLT3-ITD confers resistance to the PI3K/Akt pathway inhibitors by protecting the mTOR/4EBP1/Mcl-1 pathway through STAT5 activation in acute myeloid leukemia
2015
·
Ayako Nogami
, Gaku Oshikawa
, et al.
·
Oncotarget
·
69
PDF
Post‐transplant maintenance therapy with azacitidine and gemtuzumab ozogamicin for high‐risk acute myeloid leukaemia
2014
·
Gaku Oshikawa
, Kazuhiko Kakihana
, et al.
·
British Journal of Haematology
·
61
PDF
c-Cbl and Cbl-b Ligases Mediate 17-Allylaminodemethoxygeldanamycin-induced Degradation of Autophosphorylated Flt3 Kinase with Internal Tandem Duplication through the Ubiquitin Proteasome Pathway
2011
·
Gaku Oshikawa
, Toshikage Nagao
, et al.
·
Journal of Biological Chemistry
·
46
PDF
Enhancement of imatinib-induced apoptosis of BCR/ABL-expressing cells by nutlin-3 through synergistic activation of the mitochondrial apoptotic pathway
2010
·
Tetsuya Kurosu
, Nan Wu
, et al.
·
APOPTOSIS
·
45
Inhibition of the PI3K/Akt/GSK3 Pathway Downstream of BCR/ABL, Jak2-V617F, or FLT3-ITD Downregulates DNA Damage-Induced Chk1 Activation as Well as G2/M Arrest and Prominently Enhances Induction of Apoptosis
2013
·
Tetsuya Kurosu
, Toshikage Nagao
, et al.
·
PLoS ONE
·
43
PDF
Mechanisms for mTORC1 activation and synergistic induction of apoptosis by ruxolitinib and BH3 mimetics or autophagy inhibitors in JAK2-V617F-expressing leukemic cells including newly established PVTL-2
2018
·
Shinya Ishida
, Hiroki Akiyama
, et al.
·
Oncotarget
·
27
Proliferation and Survival Signaling from Both Jak2-V617F and Lyn Involving GSK3 and mTOR/p70S6K/4EBP1 in PVTL-1 Cell Line Newly Established from Acute Myeloid Leukemia Transformed from Polycythemia Vera
2014
·
Toshikage Nagao
, Tetsuya Kurosu
, et al.
·
PLoS ONE
·
25
PDF
Bortezomib-induced Posterior Reversible Encephalopathy Syndrome in a Patient with Newly Diagnosed Multiple Myeloma
2013
·
Gaku Oshikawa
, Akira Kojima
, et al.
·
Internal Medicine
·
23
PDF
Clinical features and risk factors for developing varicella zoster virus dissemination following hematopoietic stem cell transplantation
2014
·
Y. Umezawa
, K. Kakihana
, et al.
·
Transplant Infectious Disease
·
19
A novel MYD88 mutation, L265RPP, in Waldenström macroglobulinemia activates the NF-κB pathway to upregulate Bcl-xL expression and enhances cell survival
2015
·
T Nagao
, G Oshikawa
, et al.
·
Blood Cancer Journal
·
18
PDF
Acute promyelocytic leukemia presenting as recurrent spinal myeloid sarcomas 3 years before developing leukemia: A case report with review of literature
2019
·
Tomoko Yamashita
, Akihiko Nishijima
, et al.
·
Clinical Case Reports
·
16
PDF
Acute myeloid leukemia with t(3;21)(q26.2;q22) developing following low-dose methotrexate therapy for rheumatoid arthritis and expressing two AML1/MDS1/EVI1 fusion proteins: A case report
2017
·
Keisuke Tanaka
, Gaku Oshikawa
, et al.
·
Oncology Letters
·
16
PDF
DNA Damage Stress and Inhibition of Jak2-V617F Cause Its Degradation and Synergistically Induce Apoptosis through Activation of GSK3β
2011
·
Toshikage Nagao
, Gaku Oshikawa
, et al.
·
PLoS ONE
·
16
PDF
Clonal evolution with double Ph followed by tetraploidy in imatinib-treated chronic myeloid leukemia with e19a2 transcript in transformation
2010
·
Gaku Oshikawa
, Tetsuya Kurosu
, et al.
·
Cancer Genetics and Cytogenetics
·
14
Extranodal NK/T cell lymphoma, nasal type, of the small intestine diagnosed by double-balloon endoscopy
2009
·
Shihoko Wakabayashi
, Ayako Arai
, et al.
·
International Journal of Hematology
·
14
Molecular mechanisms for enhancement of stromal cell-derived factor 1–induced chemotaxis by platelet endothelial cell adhesion molecule 1 (PECAM-1)
2017
·
Yoshihiro Umezawa
, Hiroki Akiyama
, et al.
·
Journal of Biological Chemistry
·
11
PDF
Romiplostim with ciclosporin A in patients with aplastic anaemia naïve to immunosuppressive therapy: A phase 2/3 study
2025
·
Jong Wook Lee
, Jun Ho Jang
, et al.
·
British Journal of Haematology
·
10
Impact of prior azacitidine on the outcome of allogeneic hematopoietic transplantation for myelodysplastic syndrome
2015
·
Gaku Oshikawa
, Kousuke Yoshioka
, et al.
·
Pathology & Oncology Research
·
10
Importance of TKI treatment duration in treatment-free remission of chronic myeloid leukemia: results of the D-FREE study
2023
·
Chikashi Yoshida
, Hiroki Yamaguchi
, et al.
·
International Journal of Hematology
·
9
PDF
PECAM-1 is involved in BCR/ABL signaling and may downregulate imatinib-induced apoptosis of Philadelphia chromosome-positive leukemia cells
2012
·
NAN WU
, TETSUYA KUROSU
, et al.
·
International Journal of Oncology
·
9
PDF
Clinical Outcome of Hematopoietic Stem Cell Transplantation for Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia (Ph + ALL): Experience From a Single Institution
2013
·
Noriko Doki
, Kazuteru Ohashi
, et al.
·
Pathology & Oncology Research
·
7
[Primary multifocal osseous Hodgkin lymphoma].
2009
·
Gaku Oshikawa
, Ayako Arai
, et al.
·
PubMed
·
7
Optimizing Treatment Options for Newly Diagnosed Acute Myeloid Leukemia in Older Patients with Comorbidities
2023
·
Gaku Oshikawa
, Koji Sasaki
·
Cancers
·
6
PDF
[Bortezomib-induced tumor lysis syndrome with a remarkable elevation of LDH in a case of relapsed and therapy-resistant multiple myeloma].
2006
·
Ayako Arai
, Gaku Oshikawa
, et al.
·
PubMed
·
5
Clinical impact of CD25 expression on outcomes of allogeneic hematopoietic stem cell transplant for cytogenetically intermediate-risk acute myeloid leukemia
2014
·
Shuntaro Ikegawa
, Noriko Doki
, et al.
·
Leukemia & lymphoma/Leukemia and lymphoma
·
4
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Works count:
55
Citation count:
557
H-index:
14
I10-index:
18
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