Work

Acute promyelocytic leukemia presenting as recurrent spinal myeloid sarcomas 3 years before developing leukemia: A case report with review of literature

Year: 2019

Type: article

Abstract: The de novo myeloid sarcoma (MS) type of acute promyelocytic leukemia (APL) is rare, and clinical features may differ from extramedullary diseases in advanced APL. Many cases occur as a spinal tumor, and some occur in the absence of bone-marrow diseases or coagulation abnormalities. Fluorescence in situ hybridization analysis of MS tissue is useful for accurate diagnosis, even in preserved tissue.

Source: Clinical Case Reports

DOI: 10.1002/ccr3.1991

Authors: Tomoko Yamashita, Akihiko Nishijima, Yuma Noguchi, Kensuke Narukawa, Gaku Oshikawa, Hina Takano

Institutions: Toshiba (Japan), Tokyo Shinagawa Hospital, Musashino Red Cross Hospital

Language: English

Topic: Retinoids in leukemia and cellular processes

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,100