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Debra J. Wallace
Observed names:
D. J. WALLACE,
D. J. Wallace,
D. Wallace,
Debra J Wallace,
Debra Wallace,
Debra J. Wallace,
Wallace, Debra J.
show all 7
Institutions:
Merck & Co., Inc., Rahway, NJ, USA (United States),
Cyclerion (United States)
Observed institutions:
Merck & Co., Inc., Rahway, NJ, USA (United States),
University of British Columbia,
University of Cambridge,
MSD (UK) Limited (United Kingdom),
Cyclerion (United States)
ORCID:
0000-0001-5708-2578
Observed ORCID:
0000-0001-5708-2578
OpenAlex ID:
A5081361323
Palladium-Catalyzed Amidation of Enol Triflates: A New Synthesis of Enamides
2003
·
Debra J. Wallace
, David J. Klauber
, et al.
·
Organic Letters
·
166
Studies in polypropionate synthesis: High π-face selectivity in syn and anti aldol reactions of chiral boron enolates of lactate-derived ketones
1994
·
Ian Paterson
, Debra J. Wallace
, et al.
·
Tetrahedron Letters
·
142
Phosphine-Catalyzed Cycloadditions of Allenic Ketones: New Substrates for Nucleophilic Catalysis
2007
·
Debra J. Wallace
, Rachel L. Sidda
, et al.
·
The Journal of Organic Chemistry
·
140
CRTH2 Antagonist MK-7246: A Synthetic Evolution from Discovery through Development
2012
·
Carmela Molinaro
, Paul G. Bulger
, et al.
·
The Journal of Organic Chemistry
·
125
Reaction Development and Mechanistic Study of a Ruthenium Catalyzed Intramolecular Asymmetric Reductive Amination en Route to the Dual Orexin Inhibitor Suvorexant (MK-4305)
2011
·
Neil A. Strotman
, Carl A. Baxter
, et al.
·
Journal of the American Chemical Society
·
123
Stereocontrolled Total Synthesis of (+)-Altohyrtin A/Spongistatin 1 Financial support was provided by the EPSRC (GR/L41646), Cambridge Commonwealth Trust (Scholarship to M.J.C.), EC (Marie Curie Postdoctoral Fellowship to J.L.A.), DFG (Postdoctoral Fellowship to T.T.), NSERC-Canada (Postdoctoral Fellowship to R.M.O.), Churchill College (Research Fellowship to D.J.W.), Kingapos;s College and Sims Fund, Cambridge (Scholarship to D.Y.K.C.). We also thank Merck and AstraZeneca Pharmaceuticals for generous support, and Dr. Anne Butlin (AZ) and Dr. Nick Bampos (Cambridge) for valuable assistance.
2001
·
Ian Paterson
, David Y.-K. Chen
, et al.
·
Angewandte Chemie International Edition
·
116
Relay Ring‐Closing Metathesis—A Strategy for Achieving Reactivity and Selectivity in Metathesis Chemistry
2005
·
Debra J. Wallace
·
Angewandte Chemie International Edition
·
111
Synthesis and Antimitotic/Cytotoxic Activity of Hemiasterlin Analogues
2002
·
James A. Nieman
, John E. Coleman
, et al.
·
Journal of Natural Products
·
111
The First Large-Scale Synthesis of MK-4305: A Dual Orexin Receptor Antagonist for the Treatment of Sleep Disorder
2011
·
Carl A. Baxter
, Ed Cleator
, et al.
·
Organic Process Research & Development
·
100
Cyclopropylboronic acid: synthesis and Suzuki cross-coupling reactions
2002
·
Debra J. Wallace
, Cheng-yi Chen
·
Tetrahedron Letters
·
86
An Investigation into Causes and Effects of High Cyanide Levels in the Palladium-Catalyzed Cyanation Reaction
2004
·
Karen M. Marcantonio
, Lisa F. Frey
, et al.
·
Organic Letters
·
82
Catalytic, Enantioselective Synthesis of Taranabant, a Novel, Acyclic Cannabinoid-1 Receptor Inverse Agonist for the Treatment of Obesity
2007
·
Cheng-yi Chen
, Lisa F. Frey
, et al.
·
Organic Process Research & Development
·
79
Total synthesis of (−)-hemiasterlin, a structurally novel tripeptide that exhibits potent cytotoxic activity
1997
·
Raymond J Andersen
, John E Coleman
, et al.
·
Tetrahedron Letters
·
77
A Double Ring Closing Metathesis Reaction in the Rapid, Enantioselective Synthesis of NK-1 Receptor Antagonists
2001
·
Debra J. Wallace
, Jonathan M. Goodman
, et al.
·
Organic Letters
·
68
Convergent, Kilogram Scale Synthesis of an Akt Kinase Inhibitor
2012
·
Pintipa Grongsaard
, Paul G. Bulger
, et al.
·
Organic Process Research & Development
·
66
New Efficient Asymmetric Synthesis of Taranabant, a CB1R Inverse Agonist for the Treatment of Obesity
2009
·
Debra J. Wallace
, Kevin R. Campos
, et al.
·
Organic Process Research & Development
·
63
Studies in marine macrolide synthesis: Synthesis of a C16C28 subunit of spongistatin 1 (altohyrtin A) incorporating the CD-spiroacetal moiety
1997
·
Ian Paterson
, Debra J Wallace
, et al.
·
Tetrahedron Letters
·
63
Manipulation of the aldol adducts from lactate-derived ketones. A versatile chiral auxiliary for the asymmetric synthesis of β-hydroxy carbonyl compounds
1994
·
Ian Paterson
, Debra J. Wallace
·
Tetrahedron Letters
·
62
Development of a Fit-for-Purpose Large-Scale Synthesis of an Oral PARP Inhibitor
2011
·
Debra J. Wallace
, Carl A. Baxter
, et al.
·
Organic Process Research & Development
·
58
The stereocontrolled total synthesis of altohyrtin A/spongistatin 1: the CD-spiroacetal segment
2005
·
Ian Paterson
, Mark J. Coster
, et al.
·
Organic & Biomolecular Chemistry
·
52
Stereoselective double ring closing metathesis reactions in the synthesis of spirocyclic compounds
2000
·
Debra J Wallace
, Cameron J Cowden
, et al.
·
Tetrahedron Letters
·
50
The stereocontrolled total synthesis of altohyrtin A/spongistatin 1: fragment couplings, completion of the synthesis, analogue generation and biological evaluation
2005
·
Ian Paterson
, David Y.-K. Chen
, et al.
·
Organic & Biomolecular Chemistry
·
45
Copper-mediated reaction of 2-halopyridines with ethyl bromodifluoroacetate
2002
·
Michael S. Ashwood
, Ian F. Cottrell
, et al.
·
Tetrahedron Letters
·
43
The stereocontrolled total synthesis of altohyrtin A/spongistatin 1: the AB-spiroacetal segment
2005
·
Ian Paterson
, Mark J. Coster
, et al.
·
Organic & Biomolecular Chemistry
·
42
Development of a Phase Transfer Catalyzed Asymmetric Synthesis for an Estrogen Receptor Beta Selective Agonist
2007
·
Jeremy P. Scott
, Michael S. Ashwood
, et al.
·
Organic Process Research & Development
·
38
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Works count:
81
Citation count:
2,545
H-index:
30
I10-index:
43
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