Work

Reaction Development and Mechanistic Study of a Ruthenium Catalyzed Intramolecular Asymmetric Reductive Amination en Route to the Dual Orexin Inhibitor Suvorexant (MK-4305)

Year: 2011

Type: article

Source: Journal of the American Chemical Society

DOI: 10.1021/ja202358f

Authors: Neil A. Strotman, Carl A. Baxter, Karel M. J. Brands, Ed Cleator, Shane W. Krska, Robert A. Reamer, Debra J. Wallace, Timothy J. Wright

Institutions: Merck & Co., Inc., Rahway, NJ, USA (United States), MSD (UK) Limited (United Kingdom)

Language: English

Topic: Asymmetric Hydrogenation and Catalysis

Subfield: Inorganic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: closed

OpenAlex ID: W2003267640

FWCI: 4.944

Cites: 29

Cited by: 123

Related to: 10